ID A0A0W4ZS80_PNEJ7 Unreviewed; 418 AA.
AC A0A0W4ZS80;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 08-NOV-2023, entry version 28.
DE RecName: Full=PCI domain-containing protein {ECO:0000259|PROSITE:PS50250};
GN ORFNames=T551_01293 {ECO:0000313|EMBL:KTW31220.1};
OS Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW31220.1, ECO:0000313|Proteomes:UP000053447};
RN [1] {ECO:0000313|Proteomes:UP000053447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SIMILARITY: Belongs to the proteasome subunit S9 family.
CC {ECO:0000256|ARBA:ARBA00007454}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW31220.1}.
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DR EMBL; LFWA01000005; KTW31220.1; -; Genomic_DNA.
DR RefSeq; XP_018230210.1; XM_018373556.1.
DR AlphaFoldDB; A0A0W4ZS80; -.
DR STRING; 1408657.A0A0W4ZS80; -.
DR GeneID; 28939811; -.
DR VEuPathDB; FungiDB:T551_01293; -.
DR eggNOG; KOG1463; Eukaryota.
DR OrthoDB; 516300at2759; -.
DR Proteomes; UP000053447; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR040780; Rpn6_C_helix.
DR InterPro; IPR040773; Rpn6_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10678:SF2; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11; 1.
DR PANTHER; PTHR10678; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF18503; RPN6_C_helix; 1.
DR Pfam; PF18055; RPN6_N; 1.
DR SMART; SM00753; PAM; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000053447}.
FT DOMAIN 220..388
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 418 AA; 47726 MW; 6A5ACC7EFE4E3283 CRC64;
MQEENIYLAQ EAQEKGDFGY AERLLIEQLK KDFNTNEKEM KQHEEALIKL GELYRDQKRL
DELAKLIQES LLFLKNFAKA KTAKIVRRLI DLFSSVPGSL NLQIDVTKET IDWAKKNNRI
FLKLSLETHI VELYIKAQQY TKALQLVETL LIELKRLDDK FQLVEVYLLE SQIYYAIKNI
PKARASLTSA RTCANAIYCL PHIQTGLDLQ SGILHAEEKD YNTAYSYFYE AYEGFSASSN
PRAVSTIKYL LLCKIMLNAS SDVQSFINTK VSQKHAGRDL DAMNAVAQAH QNRSLADFEK
ALIDFKDELE DDPIVHSHLT VLYDTLLKQN LSKIIEPFSR VELTHISKLI GICITKIEEK
LSQMILDKVF HGILDQGTGC LIIFDEPAQD ATYNAALDTI KNLNTVVDLL QEKVAKLL
//
