ID   A0A0W4ZSD6_PNEJ7        Unreviewed;       316 AA.
AC   A0A0W4ZSD6;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=DNA/pantothenate metabolism flavoprotein C-terminal domain-containing protein {ECO:0000259|Pfam:PF04127};
GN   ORFNames=T551_01365 {ECO:0000313|EMBL:KTW31293.1};
OS   Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX   NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW31293.1, ECO:0000313|Proteomes:UP000053447};
RN   [1] {ECO:0000313|Proteomes:UP000053447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX   PubMed=26899007; DOI=10.1038/ncomms10740;
RA   Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA   Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA   Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA   Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA   Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA   Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA   Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT   "Genome analysis of three Pneumocystis species reveals adaptation
RT   mechanisms to life exclusively in mammalian hosts.";
RL   Nat. Commun. 7:10740-10740(2016).
CC   -!- SIMILARITY: Belongs to the PPC synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005703}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTW31293.1}.
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DR   EMBL; LFWA01000005; KTW31293.1; -; Genomic_DNA.
DR   RefSeq; XP_018230283.1; XM_018373628.1.
DR   AlphaFoldDB; A0A0W4ZSD6; -.
DR   STRING; 1408657.A0A0W4ZSD6; -.
DR   GeneID; 28939883; -.
DR   VEuPathDB; FungiDB:T551_01365; -.
DR   OrthoDB; 6287at2759; -.
DR   Proteomes; UP000053447; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.50.10300; CoaB-like; 1.
DR   InterPro; IPR035929; CoaB-like_sf.
DR   InterPro; IPR007085; DNA/pantothenate-metab_flavo_C.
DR   PANTHER; PTHR12290; CORNICHON-RELATED; 1.
DR   PANTHER; PTHR12290:SF2; PHOSPHOPANTOTHENATE--CYSTEINE LIGASE; 1.
DR   Pfam; PF04127; DFP; 1.
DR   SUPFAM; SSF102645; CoaB-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053447}.
FT   DOMAIN          174..284
FT                   /note="DNA/pantothenate metabolism flavoprotein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04127"
SQ   SEQUENCE   316 AA;  37260 MW;  AE6EED636123D436 CRC64;
     MNEFYFENNQ EPALLKEWEQ KVEEFVNIQL KNDKRVVLVT VWKSGGTAVP LESQPVRFLD
     NFSAGTRGST STEYFIKFGY SVIFLYRQYS FLPYSRSYYY GKDDFFDYFE ETQDSNGKND
     SGFKTVSRCK LNIYFSFILF LKAKLNNKLL MVPFFTITEY LFYLRMIAIN FRPLSKNAVF
     YLAAAVSDFF IPPERINDHK IHSEFPEKRL VIEFDPVPKF LAGLVEKWAP HANIVSFKLE
     TDTNLLISRA RASLQRYRHR LVIGNLLMKR KYEVVFVTDT EESWIRLSQA ESDEGIEIES
     KIVSRIVKLH NFWIQL
//