ID A0A0W4ZUD6_PNEJ7 Unreviewed; 574 AA.
AC A0A0W4ZUD6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=STI1 domain-containing protein {ECO:0000259|SMART:SM00727};
GN ORFNames=T551_00619 {ECO:0000313|EMBL:KTW31936.1};
OS Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW31936.1, ECO:0000313|Proteomes:UP000053447};
RN [1] {ECO:0000313|Proteomes:UP000053447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW31936.1}.
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DR EMBL; LFWA01000003; KTW31936.1; -; Genomic_DNA.
DR RefSeq; XP_018230628.1; XM_018372885.1.
DR AlphaFoldDB; A0A0W4ZUD6; -.
DR STRING; 1408657.A0A0W4ZUD6; -.
DR GeneID; 28939140; -.
DR VEuPathDB; FungiDB:T551_00619; -.
DR eggNOG; KOG0548; Eukaryota.
DR OrthoDB; 1343678at2759; -.
DR Proteomes; UP000053447; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.260.100; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR041243; STI1/HOP_DP.
DR InterPro; IPR006636; STI1_HS-bd.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR22904:SF523; STRESS-INDUCED-PHOSPHOPROTEIN 1; 1.
DR PANTHER; PTHR22904; TPR REPEAT CONTAINING PROTEIN; 1.
DR Pfam; PF17830; STI1-HOP_DP; 2.
DR Pfam; PF07719; TPR_2; 2.
DR Pfam; PF13181; TPR_8; 3.
DR SMART; SM00727; STI1; 2.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053447};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 2..35
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 36..69
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 70..103
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 140..179
FT /note="STI1"
FT /evidence="ECO:0000259|SMART:SM00727"
FT REPEAT 320..353
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 380..413
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 414..447
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 521..560
FT /note="STI1"
FT /evidence="ECO:0000259|SMART:SM00727"
FT REGION 200..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..249
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 65538 MW; 9033092276D2C1FA CRC64;
MSEEIRQEAN SLFSAKKYEE AIKMYTEAIT LEPGNHVLYS NRSACYASLK NFDEALKDAL
KCIEINPNWA KGWSRKGVAL HGKGNLEESK HAYEKGLELE PENQQIKAAL KTVEESISRD
FSKNFQKNDP FTQIAMKLNS PDFLSKVASN PKTSGLLSNP QFMEKLKKIQ ENPRIIFQEL
NDPNMASILP LLLGLDTDTS NHINGDSKET HSPPSEKSSE SEVEADQELM EEDEDTKAQR
ENKEKAEKEK ALGNECYKKR QFEKSVQHYL SAWEIYKDIT YLTNCSAAYY EDGKYEECIK
CCEEAITYGR EVLADFKLIA RAFGRIGTAY MKQENYELAI KNFNSSLTEH RTPDILKKLR
EAEKIKEEKD RLAYIDHNKA DEAREQGNKL FKEGDFGGAI KMYSEMIKRS PDDPRGYGNR
AAAYIKVMSM VEALKDCEKA ISLDPNFTKA YIRKASCYFT MKEYNKCIDA CHSATKADEN
SNNKGMHAKE IEAQLQKCMS AMYAQRENET EEQTLQRIQN DPEILSILQD PVMQSILNQA
RENPAALEEH MKNAQVASKI QKLIHSGVIK LSRR
//
