ID A0A0W4ZVU3_PNEJ7 Unreviewed; 378 AA.
AC A0A0W4ZVU3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Pre-mRNA polyadenylation factor Fip1 domain-containing protein {ECO:0000259|Pfam:PF05182};
GN ORFNames=T551_00566 {ECO:0000313|EMBL:KTW32476.1};
OS Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW32476.1, ECO:0000313|Proteomes:UP000053447};
RN [1] {ECO:0000313|Proteomes:UP000053447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the FIP1 family.
CC {ECO:0000256|ARBA:ARBA00007459}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW32476.1}.
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DR EMBL; LFWA01000002; KTW32476.1; -; Genomic_DNA.
DR RefSeq; XP_018231168.1; XM_018372832.1.
DR AlphaFoldDB; A0A0W4ZVU3; -.
DR STRING; 1408657.A0A0W4ZVU3; -.
DR GeneID; 28939087; -.
DR VEuPathDB; FungiDB:T551_00566; -.
DR eggNOG; KOG1049; Eukaryota.
DR OrthoDB; 449619at2759; -.
DR Proteomes; UP000053447; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR007854; Fip1_dom.
DR PANTHER; PTHR13484; FIP1-LIKE 1 PROTEIN; 1.
DR PANTHER; PTHR13484:SF0; PRE-MRNA 3'-END-PROCESSING FACTOR FIP1; 1.
DR Pfam; PF05182; Fip1; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053447}.
FT DOMAIN 129..169
FT /note="Pre-mRNA polyadenylation factor Fip1"
FT /evidence="ECO:0000259|Pfam:PF05182"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..59
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 41632 MW; 1958553274FDF21F CRC64;
MSDDEEDRYL YGKEETPKTV FSSEAGRDTP DLGKDQEMQD VSKDVADESE EDEYESDSDI
EFVIETKPGQ RAEPLSRPAP YSGVRVSAPI KGADKVHLST QKTEPSAPKP SGVDVYHVAE
WNGKSLFQLD MDSIEDKPWN KPGADITDYF NYGFDEFTWM AYCAKQIGIR EEFAPQKFMQ
MMGQMSGADI MSMAPNMQVM MAAGGFPGMQ GISGMHPDMM PMMGMGMSDM SGFVMNMGQM
GQMGFQQFPP GLNTMMSDSQ SGQSVQGKQM PYMHTPYNMQ SYGGYNQMQS QYNLQMQGSK
PTPSGPKAHN VDGVKALSNE RTASPGNHKQ ELVSGSSKDS HETTEHISSN SQSRSSGRSS
VQHRSKSSSS SGKSRSNH
//
