ID A0A0W4ZWB5_PNEJ7 Unreviewed; 609 AA.
AC A0A0W4ZWB5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN ORFNames=T551_00128 {ECO:0000313|EMBL:KTW32643.1};
OS Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW32643.1, ECO:0000313|Proteomes:UP000053447};
RN [1] {ECO:0000313|Proteomes:UP000053447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW32643.1}.
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DR EMBL; LFWA01000001; KTW32643.1; -; Genomic_DNA.
DR RefSeq; XP_018231335.1; XM_018372395.1.
DR AlphaFoldDB; A0A0W4ZWB5; -.
DR STRING; 1408657.A0A0W4ZWB5; -.
DR GeneID; 28938650; -.
DR VEuPathDB; FungiDB:T551_00128; -.
DR eggNOG; KOG0318; Eukaryota.
DR OrthoDB; 5476506at2759; -.
DR Proteomes; UP000053447; Unassembled WGS sequence.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19856:SF0; WD REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR19856; WD-REPEATCONTAINING PROTEIN WDR1; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00320; WD40; 9.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053447};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 54..86
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 185..226
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 230..271
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 318..354
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 478..528
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 487..528
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 609 AA; 67247 MW; FFC8E7044926C0D0 CRC64;
MLIEKVSIWS PLPSTTRASP VHLSSHPDGT KIAYASNKSI YLRSIDNPVD TVQYRGHLAQ
TTVAKFSPSG YYVASGDSQG NVRVWSCVGE ENVLKLEKKV ISGRINDLTW DSESKRIIAV
GDGQERFGHA FTFDTGNSVG EISGHSEIAN AVSIRHQRPY RAVTVSDDTS VVFYHGPPFL
YHSISRSHKK YVYDVSFSPN GALFCTVGGD SKIIIYDGKD GIMIKEFSSE DGHKGSIFAL
SWSPDSRYLL TSSADHTCKI WDVETQRVTE TWIFSETVSV LDQQVGNLWT PSNKILSLSF
SGDLNYLSRS QKKPTRVVQG HQKSITTGGL SEDGSTFFTA SYDGLVCGWD VSTGFAKSLK
DGSTHTNQVI QIHPCHDKMF SIGMDDTLRT LDTKLLIYEG DPIETGSLPK GITYILEKDY
FKIIVTVSNI QVFENNKRII LNETSFQPSS VDRNKTNYEF SIGAENGNIY FFEFNPNQKK
ITGTNKITLN RFAVTSLAYS PNGQYLAAGD GSGKIILYDA KTKQIITNLW GFHVGKITSI
SWNPTSTHIC SASLDTHLYI YSVFTPDKHV AAKNAHLGGV SSVVWLSSNQ VLSTGADACV
KQWRVTLNA
//
