ID A0A0W7W0K1_9HYPO Unreviewed; 876 AA.
AC A0A0W7W0K1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=TGAM01_v204855 {ECO:0000313|EMBL:PON26379.1}, TGAMA5MH_00121
GN {ECO:0000313|EMBL:PNP48962.1};
OS Trichoderma gamsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=398673 {ECO:0000313|EMBL:PNP48962.1, ECO:0000313|Proteomes:UP000236546};
RN [1] {ECO:0000313|EMBL:PON26379.1, ECO:0000313|Proteomes:UP000054821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6085 {ECO:0000313|EMBL:PON26379.1,
RC ECO:0000313|Proteomes:UP000054821};
RX PubMed=26893428;
RA Baroncelli R., Zapparata A., Piaggeschi G., Sarrocco S., Vannacci G.;
RT "Draft Whole-Genome Sequence of Trichoderma gamsii T6085, a Promising
RT Biocontrol Agent of Fusarium Head Blight on Wheat.";
RL Genome Announc. 4:e01747-15(2016).
RN [2] {ECO:0000313|EMBL:PNP48962.1, ECO:0000313|Proteomes:UP000236546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A5MH {ECO:0000313|EMBL:PNP48962.1,
RC ECO:0000313|Proteomes:UP000236546};
RA Gardiner D., Kazan K., Vos C., Harvey P.;
RT "Genomes of Trichoderma spp. with biocontrol activity.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:PON26379.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=T6085 {ECO:0000313|EMBL:PON26379.1};
RA Baroncelli R.;
RT "Trichoderma gamsii strain T6085, whole genome shotgun sequencing
RT project.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC subfamily. {ECO:0000256|ARBA:ARBA00010907}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNP48962.1}.
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DR EMBL; MTYH01000001; PNP48962.1; -; Genomic_DNA.
DR EMBL; JPDN02000014; PON26379.1; -; Genomic_DNA.
DR RefSeq; XP_018665241.1; XM_018801448.1.
DR AlphaFoldDB; A0A0W7W0K1; -.
DR STRING; 398673.A0A0W7W0K1; -.
DR GeneID; 29981531; -.
DR OrthoDB; 124901at2759; -.
DR Proteomes; UP000054821; Unassembled WGS sequence.
DR Proteomes; UP000236546; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054821}.
FT DOMAIN 24..105
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 413..451
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 876 AA; 95856 MW; 0DECB108ADAA929B CRC64;
MSGSEINTVL ANSLSADANL RIAAEQQLTQ AAESNFPLYL ATLVQELAND QAQGSIRAAA
GIALKNAFTA RDFARQQELQ SKWLQQTDEE TKNRVKQLTL QTLSSSNTQA GNAAAQVISS
IAAIELPRGQ WTDLLSFLVK NVSEGADHQK QSSLTTIGYI CESQDPELRL ALVAHSNAIL
TAVVQGARKE ETNGEVRLAA ITALGDSLEF VANNFKHEGE RNYIMQVVCE ATQADDSRIQ
QGAFGCLNRI MGLYYENMRF YMEKALFGLT ILGMKSEDED VAKLAVEFWS TVCEEEVSIE
DDNSQVETAD QMRPFYNFAR VAANEVVPVL LTLLTKQDED ATDDEYNLSR AAYQCLQLYS
QAVNSTIIGP VLAFVEANLR SDDWHNRDAA VSAFGAIMEG PDEKVLEPIV KQALPVLITM
MDDQSLQVKD STAYALGRVT EACSEAIDAQ QHLPTLIASL FKGLISNAKM APSCCWALMN
LAERFAGDFG AASNPITPHF NQAVSSLLDV TARQDTDTSV RTAAYEVLNV FVQNAASESL
SAIASLSDVI IKRLEETIPL QSQVVSVEDK LTLEEMQNSL CTVLQAIISR LDKEITPQGD
RIMQVLLQIL STIGGKSSVP EAIFATISAL STTMEEDFIK YMEAFVPFLY NALGNQDEPS
LCSMAIGLVS DITRSMGERS QPYCDNFMNY LLNNLRSTTL ANQFKPAILQ CFGDIAGAIG
GHFETYLSVV AQVLEQASTV TATPEGPDEM FYYVISLREG IMDAWGGIIG AMKSSGKTQV
LQQYVPSIFQ LLNLVGSDAN RSESLMRAAM GVIGDLADAY PNGELIDAFR QGWLTTMIKE
TKTNRDFQPR TIETARWARE QVKRQLGGSQ GVIAQS
//
