ID   A0A0W7WR74_9ACTN        Unreviewed;      1229 AA.
AC   A0A0W7WR74;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:KUF13085.1};
GN   ORFNames=AT728_37480 {ECO:0000313|EMBL:KUF13085.1};
OS   Streptomyces silvensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF13085.1, ECO:0000313|Proteomes:UP000054804};
RN   [1] {ECO:0000313|EMBL:KUF13085.1, ECO:0000313|Proteomes:UP000054804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF13085.1,
RC   ECO:0000313|Proteomes:UP000054804};
RA   Johnston C.W., Li Y., Magarvey N.A.;
RT   "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT   novel hormone antagonists.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUF13085.1}.
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DR   EMBL; LOCL01000083; KUF13085.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0W7WR74; -.
DR   STRING; 1765722.AT728_37480; -.
DR   Proteomes; UP000054804; Unassembled WGS sequence.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.200; -; 2.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006558; LamG-like.
DR   InterPro; IPR042837; PTX3.
DR   PANTHER; PTHR46943; PENTRAXIN-RELATED PROTEIN PTX3; 1.
DR   PANTHER; PTHR46943:SF1; PENTRAXIN-RELATED PROTEIN PTX3; 1.
DR   Pfam; PF13385; Laminin_G_3; 2.
DR   SMART; SM00560; LamGL; 2.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:KUF13085.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:KUF13085.1};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transferase {ECO:0000313|EMBL:KUF13085.1}.
FT   DOMAIN          804..957
FT                   /note="LamG-like jellyroll fold"
FT                   /evidence="ECO:0000259|SMART:SM00560"
FT   DOMAIN          1048..1218
FT                   /note="LamG-like jellyroll fold"
FT                   /evidence="ECO:0000259|SMART:SM00560"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          201..252
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          961..1018
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1229 AA;  132116 MW;  3843C4AFCCDBCA29 CRC64;
     MRPGPANAPT AGQSAAERAA ATGEPVEVIS ERSEYTTTMA NPDGTFVLTQ ATEPQRARDA
     AGAWRDIDAT LEKRSDGTVG PKSAVVDLAF SGGGEGSGLL SLGTGDQRIR LGWPTPLPEP
     SLDGATATYA NVPVKDVDLQ LTATAEGYRE VLVVKTAEAA ASPELEKVKL TARGEGLSLV
     PGEGGGLRAV DADGNALFRG PSGQMWDSAG DTVAAPRKGL RAGGTEEKPA AGGGSEDPAQ
     PGSGDTTADL PVAVGDGEVS VTPDLDLLRG EKTVYPVFID PSVGLGKSEW TKLSSDGDKF
     WKFSEPKGVG RCGIADGYYC DLGGYTDRMY FEFGASKLAG KHVLDATFRA YETWSYNCNP
     HWVDLERTDN ISEGTRWPGP KQLNQMGDRY VSAGRGNLCS PEQPNSWIEF NDNPAEKDED
     LTTTVRALAD GKMSRLTLML RAKDESDPRA WKRFDNNAEL KVWYMHKPGV PSSVGAVPGT
     GNSRAQCRPA KDPVTVTVDT PKVRARAQTK VQPREGEEKG ALQVEFVMER SSTDTTSGSW
     STVWTDYKPD RGSWTSDGVM QEAVTTNRAD GGLYRFKART QSHWVYGGKK GDLFSPYSKW
     CYLRIDSTAP KAPTIHSLLP YKECTTNDCI PRGGPGRPGK FHFSPNAADR DVESYRWRLL
     TSDADETKTV EAESHQAIVS LKPGLSGTQT LAVEASDLKK DKEGRVRWGP PAEFDFKVGL
     LDGTTGRWRF NDAGPGSDKT VANDTGEVGA RHDVVLRDAG GTGWSTMGRR GAGDYALRLN
     DNVSDPDKRV GYASTDGVPV NTQDSYTVSA WAYLTDAAAN RTVLSAPGEH GSAFTLYYSS
     ALKKWVFNRT DQDRNGATYI RSTATADNPP LKVWTHLTGV FDTQRNGDKS DDTIQLFVNG
     QPQGKPVVLA DEASTYEPWT ADRNMMVGRA KVGGDYGDYF MGRVDEVAVW QDALEPPQIR
     EEHRLERKGA PSNELVSHWD ATISSGDRVS ESPEDPDDPN STGFPYRRGP LDLSGSGARL
     TGEDATSLVL DGKNGYASAA GPVVDETGSF TVSARVRLTK SEFAGKTVGY RGLVAGQATP
     VGKESSWALW VEKVADDTYQ WKFGRTAVNS DGKIIATAVA PAEDVIGDKE WDTWVDVTGV
     FDAGVDFTDD EGDQRFGVAR LYVGQFAQQG EDDAGLAKAQ QGAGSLTVGR GSAKGTTAHY
     LPGDLAKLRV WVGAMSQEQV TEQIAEPST
//