ID A0A0W7WTF4_9ACTN Unreviewed; 496 AA.
AC A0A0W7WTF4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Glutamate synthase {ECO:0000313|EMBL:KUF13861.1};
GN Name=gltD {ECO:0000313|EMBL:KUF13861.1};
GN ORFNames=AT728_00935 {ECO:0000313|EMBL:KUF13861.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF13861.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF13861.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF13861.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF13861.1}.
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DR EMBL; LOCL01000062; KUF13861.1; -; Genomic_DNA.
DR RefSeq; WP_058851618.1; NZ_LOCL01000062.1.
DR AlphaFoldDB; A0A0W7WTF4; -.
DR STRING; 1765722.AT728_00935; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 2.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 38..69
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 496 AA; 52472 MW; D0BDB06EDF1AB2A6 CRC64;
MADPKGFMRH ARREWPRRPV GERVKDWDEV YVPGGVLPFV EQQAERCMDC GVPFCHEACP
LGNLVPEWND LVSRADWHAA AERLHATNNF PEFTGRLCPA PCEAGCVLAI NQPAVTIKNV
EAAVADRVWA DGLAPPRPPE RLSGKSVGVV GSGPAGLAAA QQLTRAGHTV VVYERDDRPG
GLLRYGIPAF KMEKAHLERR LAQLRAEGTR FRTSTAVGRD IGAARLRARH DAVVLAVGAT
AWRELPVPGR ALAGVVQAME YLPPANRVCE GDLDVSPLSA AGKHVVIVGG GDTGADCLGT
AVREGAASVT QVDIRVLPPA ERDEAVDPWP VYPTVHRVSP AHEEAGELRF AQDPDADARL
FAASALRFSG DGAGRVRAVH LGGVDARRRP VPGAERTLRA DLVLLALGFE GPEVAAGGAV
AELGVAVTRD GTVARDEEYA TDVPGVYAAG DAGRGQSLVV WAIAEGRAVA AAVDRHLMGA
TSLPSPVTAS TRPLRA
//
