ID A0A0W7WYR2_9ACTN Unreviewed; 374 AA.
AC A0A0W7WYR2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:KUF15705.1};
GN ORFNames=AT728_13275 {ECO:0000313|EMBL:KUF15705.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF15705.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF15705.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF15705.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF15705.1}.
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DR EMBL; LOCL01000042; KUF15705.1; -; Genomic_DNA.
DR RefSeq; WP_058849940.1; NZ_LOCL01000042.1.
DR AlphaFoldDB; A0A0W7WYR2; -.
DR STRING; 1765722.AT728_13275; -.
DR OrthoDB; 9782387at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 73..283
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 374 AA; 41155 MW; 003D1704EB124393 CRC64;
MAHALIASPF LDGHLLLRPG ARSGARIPAD RYEGIRQAYA DGEALPTWAV QAAADAWGMD
LKGQPVQGTV LVREPSPYGY CRASWEINLG CNFGCKHCYL GERPFSGLSW EGKVRLLDIM
REAGVLWLQI TGGEPTMDPH FQGAYRYAWQ AGMMLTISTN GSLLWRPDLL KLFRDCPPYR
LVISMYGASE ESFDTLTQRR GAWKAFRRGM DAAREAGLPL RINVVVTEDN ASEADEMTAL
AEGWNVENHA YTNMTPTIYG GGEPLLAQST VHLRQRKPFA GCNAGHTFFH ADPHAKVSIC
KVGRDDQIDL MAEGVDGLIR LGAIADRLML RTGGCEGCAL SGTCRVCRPL AKHYQEAKAP
LHNYCQHGDK ENAS
//
