ID A0A0W7WZF1_9ACTN Unreviewed; 254 AA.
AC A0A0W7WZF1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Transport permease protein {ECO:0000256|RuleBase:RU361157};
GN ORFNames=AT728_13030 {ECO:0000313|EMBL:KUF15927.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF15927.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF15927.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF15927.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361157};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU361157}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC {ECO:0000256|RuleBase:RU361157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF15927.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LOCL01000042; KUF15927.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W7WZF1; -.
DR STRING; 1765722.AT728_13030; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR047817; ABC2_TM_bact-type.
DR InterPro; IPR000412; ABC_2_transport.
DR PANTHER; PTHR43027; DOXORUBICIN RESISTANCE ABC TRANSPORTER PERMEASE PROTEIN DRRC-RELATED; 1.
DR PANTHER; PTHR43027:SF2; TRANSPORT PERMEASE PROTEIN; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR PIRSF; PIRSF006648; DrrB; 1.
DR PROSITE; PS51012; ABC_TM2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU361157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361157};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361157};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361157}; Transport {ECO:0000256|RuleBase:RU361157}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 60..82
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 103..130
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 136..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 171..190
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 226..244
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT DOMAIN 24..247
FT /note="ABC transmembrane type-2"
FT /evidence="ECO:0000259|PROSITE:PS51012"
SQ SEQUENCE 254 AA; 26644 MW; B422AB7D7FC2362C CRC64;
MTTPAGRLLA LARAELTLLG RAKGTLFAAL FVPLVVPFTM KSAVKNMDLD GTGLSIGSVL
LPSAVAFSLL FAVYSALVSV YAARREELVL KRLRTGEVRD VEILAGAALP SVAIGLVQSL
VLMGMCAALL DVGAPGAAHY VVLGLVLGLV MFPLLAAVTS IVSRSVESAQ VMVMPLLFAS
MLGSGVVLPL EVMPDKLASV CELLPLSPVI ALIRGGWTGE LGAGEGLRAV LIAVAWIALG
VFAVKRWFRW EPRR
//
