ID A0A0W7X0L2_9ACTN Unreviewed; 492 AA.
AC A0A0W7X0L2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Ornithine decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AT728_11125 {ECO:0000313|EMBL:KUF16371.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF16371.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF16371.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF16371.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF16371.1}.
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DR EMBL; LOCL01000038; KUF16371.1; -; Genomic_DNA.
DR RefSeq; WP_058849189.1; NZ_LOCL01000038.1.
DR AlphaFoldDB; A0A0W7X0L2; -.
DR STRING; 1765722.AT728_11125; -.
DR OrthoDB; 9815233at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR CDD; cd00615; Orn_deC_like; 1.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR43277:SF4; ARGININE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 7..301
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 416..472
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
SQ SEQUENCE 492 AA; 52978 MW; 16567ADA002C25AA CRC64;
MDHSEAPVLD ALTAYQAEEQ LPFTPPGHKQ GRGADPRVRA ALGDAVFGAD VLAVSGLDDR
TTSQGILKHA QELMADAVGA EHTFFSTCGS SLSVKAAMLS VAGPHEKLLI GRDVHKSVVA
GLIIAGIRPV WVDPQWDPDL HLAHPPAPEA FRSAFEEHPD AQGALVTSPT PYGTCADIGA
IAALCHERGV PLIVDEAWGA HLPFHPDLPT WAMDAGADLC VTSVHKMGAG LEQGSVFHLQ
GDLVSAPTLA ARADLLDTTS PSVLIYAGLD GWRRQMMEQG RELLGEALGR ARRVRAAIEE
IEGLHVNDRD DFCGEGRAFD LDPFQIFIDL SEVKFNGYDA ADWMRRHHHI NLHTSDHRRI
NAQLTHADDE TTTARLLDGL RDLVAHADEL PRAPEIRIPA PGDLRLQQAS LPRDAFFGQV
EQIPADQAVG RICAEMLTPY PPGIPAALPG ERLDQAVVDY LRTGAEAGML IPDAADSTIA
TIRVSVHDVD AD
//
