ID A0A0W7X1E1_9ACTN Unreviewed; 771 AA.
AC A0A0W7X1E1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Salicylyl-CoA 5-hydroxylase {ECO:0000313|EMBL:KUF16669.1};
GN ORFNames=AT728_12570 {ECO:0000313|EMBL:KUF16669.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF16669.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF16669.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF16669.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF16669.1}.
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DR EMBL; LOCL01000038; KUF16669.1; -; Genomic_DNA.
DR RefSeq; WP_058849485.1; NZ_LOCL01000038.1.
DR AlphaFoldDB; A0A0W7X1E1; -.
DR STRING; 1765722.AT728_12570; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0003959; F:NADPH dehydrogenase activity; IEA:InterPro.
DR CDD; cd02932; OYE_YqiM_FMN; 1.
DR Gene3D; 3.30.9.20; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR001155; OxRdtase_FMN_N.
DR InterPro; IPR044152; YqjM-like.
DR PANTHER; PTHR43303:SF3; BLR3436 PROTEIN; 1.
DR PANTHER; PTHR43303; NADPH DEHYDROGENASE C23G7.10C-RELATED; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF00724; Oxidored_FMN; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 2..320
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 384..717
FT /note="NADH:flavin oxidoreductase/NADH oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00724"
FT REGION 733..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 83420 MW; ECCD6EAD014A21A2 CRC64;
MGGGPGGLYA AALLKRLGPE REVTVWERNA PDDTFGFGVV LSDETLGGIE HADPVVYAAL
RREFVRWDDI DIVHRGTRHT SGGHGFAALG RRTLLAVLHE RCRDLGVDLR FRTEAPPAAE
LATAYDLVIA ADGVHSATRG THADVFGPTV TPHRCRYIWL AADFAFDAFR FEIAETEHGV
MQLHGYPYEA ATEAGPGAST VIVEMREEVW RAAGFADLDP AQSVERCAKL FTDTLGGRPL
RSNNSSWLTF RTVVNDRWSH GNTVLLGDAA HTAHFSIGSG TKLAVEDALA LVACLQEQPD
LPAALTAYEA ERRPVVASTQ RAAHASLQWF EELPLYLDQP PRQFAFNLLT RSRRVTHDNL
RLRDARFTET VERDFGCPPG TPPMFTPFRL RDLELRNRVV VSPMDMYSAE DGVPGDFHLV
HLGARALGGA GLVMTEMVCV SSHGRITPGC AGLYTDEQAA AWTRIVDFAH TRAPGTALGV
QLGHSGRKGS TKLMWDGIDE PLPTGNWPLV APSALPYGPT SQTPEALDAA GLAAVREEFT
AAARRAADCG FDLLELHCAH GYLLSSFLSP LTNHRTDAYG GSLDARLRFP LEVFDAVRDV
WPASRPMTVR ISATDWADGG TTADDAVAVA RAFAAHGADA IDVSTGQVVP GERPAHGRSY
QTPFADRIRN ETHVPVVAVG AISSWDDVNS LILAGRTDLC ALARPHLYDP HWTLHAAAEQ
GYAGPGVSWP VQYRAGSRRP QTGRTDGPKP RLSLEAEAGA LPGAPQARPF P
//
