ID   A0A0W7X1Y0_9ACTN        Unreviewed;       387 AA.
AC   A0A0W7X1Y0;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=GCN5 family acetyltransferase {ECO:0000313|EMBL:KUF16880.1};
GN   ORFNames=AT728_23080 {ECO:0000313|EMBL:KUF16880.1};
OS   Streptomyces silvensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF16880.1, ECO:0000313|Proteomes:UP000054804};
RN   [1] {ECO:0000313|EMBL:KUF16880.1, ECO:0000313|Proteomes:UP000054804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF16880.1,
RC   ECO:0000313|Proteomes:UP000054804};
RA   Johnston C.W., Li Y., Magarvey N.A.;
RT   "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT   novel hormone antagonists.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homohexamer; trimer of dimers. {ECO:0000256|HAMAP-
CC       Rule:MF_01812}.
CC   -!- SIMILARITY: Belongs to the acetyltransferase Eis family.
CC       {ECO:0000256|ARBA:ARBA00009213, ECO:0000256|HAMAP-Rule:MF_01812}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUF16880.1}.
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DR   EMBL; LOCL01000036; KUF16880.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0W7X1Y0; -.
DR   STRING; 1765722.AT728_23080; -.
DR   Proteomes; UP000054804; Unassembled WGS sequence.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:UniProtKB-UniRule.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 2.
DR   Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR   HAMAP; MF_01812; Eis; 1.
DR   InterPro; IPR041380; Acetyltransf_17.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR025559; Eis_dom.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR022902; NAcTrfase_Eis.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   PANTHER; PTHR37817; N-ACETYLTRANSFERASE EIS; 1.
DR   PANTHER; PTHR37817:SF1; N-ACETYLTRANSFERASE EIS; 1.
DR   Pfam; PF17668; Acetyltransf_17; 1.
DR   Pfam; PF13527; Acetyltransf_9; 1.
DR   Pfam; PF13530; SCP2_2; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF55718; SCP-like; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315, ECO:0000256|HAMAP-
KW   Rule:MF_01812}; Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW   Rule:MF_01812}.
FT   DOMAIN          1..130
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
SQ   SEQUENCE   387 AA;  42315 MW;  53B84A6EBD3E6CDF CRC64;
     MVTTTYGQDW REGALRSARS VIEPARTLAA YDGRDIVGGA SVYGRVLTVP GARTPVAGVT
     LVAVLPTHRR RGILTAMMRR QLTELHESGG EAIAALNAAE ATIYGRFGYA AASHLARIRG
     DKRDMALRAD ADPGPGTLRL LDADRARPLL EKIHDTARLR TVGWVDRAEK YWDARLHDPE
     HARHGATALR FAVHSEPGGE ATGYALYRSE GRTVQIVELV ATTRQSYASL WRYFIDLDAH
     DHLTYEGAVD EPLPHLLRDP RAVRTTVVDN LWVRLVDVGR ALTARRYPAG LDVVLEVEDT
     FCPWNTGRHH LRAEGKTVTC ERTRARADLR LSAAELGAAY LGGPTLTALA AAGRVQELRP
     GALAAASRAF RGEREPFHVS GGAFPAF
//