ID A0A0W7X3H8_9ACTN Unreviewed; 355 AA.
AC A0A0W7X3H8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KUF17291.1};
GN ORFNames=AT728_15835 {ECO:0000313|EMBL:KUF17291.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF17291.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF17291.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF17291.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF17291.1}.
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DR EMBL; LOCL01000034; KUF17291.1; -; Genomic_DNA.
DR RefSeq; WP_058848554.1; NZ_LOCL01000034.1.
DR AlphaFoldDB; A0A0W7X3H8; -.
DR STRING; 1765722.AT728_15835; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 355 AA; 37734 MW; 49EA849D6723771E CRC64;
MAGIGIKDVA ARAGVSVATV SRVLNAHTSV SPAARERVLA AVEALGYRPN ALARSLRTDQ
TRTLGLIISD VLNPYFTALA RSVEEEARAL GYSIVFGNAD ERPELQDHHI RTLLDRRIDG
LLVSPADGGS PLVLDAARAG TPMVFVDRWI PGADVPVVRS DGRAAVRDLV AHLHGLGHRR
LAIIAGPAAT TTGSERVAAF REALAAYGIA LPDAYIGQGD FQAASGRRAT ERFLALPEPP
EVVFAADNLM ALGALDAIRA RGLRVPHDIA LAAFDDIPWF VHTDPPLTAI AQPTEELGRA
AVRALTDLIE GRTPESVTLP ARLVVRNSCG ERTTTAATRA TLETRATRAT RRSDA
//
