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Database: UniProt
Entry: A0A0W7X8H4_9ACTN
LinkDB: A0A0W7X8H4_9ACTN
Original site: A0A0W7X8H4_9ACTN 
ID   A0A0W7X8H4_9ACTN        Unreviewed;       222 AA.
AC   A0A0W7X8H4;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=RNA polymerase sigma factor 70 region 4 type 2 domain-containing protein {ECO:0000259|Pfam:PF08281};
GN   ORFNames=AT728_21730 {ECO:0000313|EMBL:KUF19183.1};
OS   Streptomyces silvensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF19183.1, ECO:0000313|Proteomes:UP000054804};
RN   [1] {ECO:0000313|EMBL:KUF19183.1, ECO:0000313|Proteomes:UP000054804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF19183.1,
RC   ECO:0000313|Proteomes:UP000054804};
RA   Johnston C.W., Li Y., Magarvey N.A.;
RT   "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT   novel hormone antagonists.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUF19183.1}.
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DR   EMBL; LOCL01000028; KUF19183.1; -; Genomic_DNA.
DR   RefSeq; WP_058846673.1; NZ_LOCL01000028.1.
DR   AlphaFoldDB; A0A0W7X8H4; -.
DR   STRING; 1765722.AT728_21730; -.
DR   OrthoDB; 3608473at2; -.
DR   Proteomes; UP000054804; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT   DOMAIN          156..199
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   222 AA;  25415 MW;  2D7E33BAF0F5D1DA CRC64;
     MWGRKEARRS EDEGAELHGQ EVTPGEALEF PQQKRRPSHT PVQPLTAVEQ ERYDQFYRSE
     FTSLTRHVIF LGATVEEAKD AAQSSLVDLL MNWRTVRSPR AWCRKAAAHH FMRNDIRINR
     SLASARRSLT SDEAEAYSLS SPLEDWEFVI TFVETHLTGV QRQVIAWHID GFEPQEIAVQ
     LRMTPATVRS NLRHARKKLA SVLVTDHPEL AKSMGDAEGK RK
//
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