ID A0A0W7X8U2_9ACTN Unreviewed; 318 AA.
AC A0A0W7X8U2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:KUF19333.1};
GN ORFNames=AT728_30430 {ECO:0000313|EMBL:KUF19333.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF19333.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF19333.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF19333.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF19333.1}.
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DR EMBL; LOCL01000027; KUF19333.1; -; Genomic_DNA.
DR RefSeq; WP_058846489.1; NZ_LOCL01000027.1.
DR AlphaFoldDB; A0A0W7X8U2; -.
DR STRING; 1765722.AT728_30430; -.
DR OrthoDB; 3727682at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08267; MDR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 13..315
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 318 AA; 33100 MW; 8A78AE49FB064FF8 CRC64;
MSDMRAVLFD RYGPPEVLYV GTRPTPSRTP EQILVRVHAV GVNGGELLDR AGKLRLVTGR
RFPRATGIDF VGEVAEAGAT GGGVREGDRV WGLLGRRTGS MAEYVAVDRH QVAPAPGNLT
AVQAVSLLAG GTTAVTALRE KAGLKPGERL LVRGGSGGVG SVAVQVGKVF GARVGALAGG
RNLDFVRGLG ADEAWDHRTT PLSALGRFDV IMDTAGTRLR DVRRLLAPGG RMVAIAPDPA
EPLAGLAAVL ASTVHGSGRI RVFSGNPRSD LLTEVTRYAE HGDIVPVVDT VHPLDGVADA
HRALAAGGVR GKHVVRIV
//
