ID A0A0W7XAL3_9ACTN Unreviewed; 369 AA.
AC A0A0W7XAL3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:KUF19799.1};
GN ORFNames=AT728_05530 {ECO:0000313|EMBL:KUF19799.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF19799.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF19799.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF19799.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF19799.1}.
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DR EMBL; LOCL01000026; KUF19799.1; -; Genomic_DNA.
DR RefSeq; WP_058846298.1; NZ_LOCL01000026.1.
DR AlphaFoldDB; A0A0W7XAL3; -.
DR STRING; 1765722.AT728_05530; -.
DR OrthoDB; 5195079at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08244; MDR_enoyl_red; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR PANTHER; PTHR48106:SF13; QUINONE OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 10..367
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 214..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 37541 MW; 43509E052976C309 CRC64;
MHAIRLHAFG PAENLVHETV EDPKPEAGQV RIAVAAAGVH LLDTAIRQGD KGPAPELPAL
PTIPGREVAG TVESVGAGVD ADWLGKRVVA HIGFAPGGYA ELTVTDVARL HELPEDLDFA
EAVALIGTGR TTMGILQFVE LDGRSVVVVP AAAGGIGTLL VQYAKHAGAT VVGLAGGEAK
VARARAGGAD LAVDYTDAGW PEVVRTFLKG LEGPTGFTER EGLTGDKEHG GSEGSEGPEG
PEGLGAGQQV SVTHVLDGVG GATGRAAVEL LGAGGVHVTF GWSAKEGPVE LGEEERAARG
ITQINPLGPA MLAKAGGENP IRVLELAALR AYAGGYFTPA VQRFPLAEAA SAHRALESRG
TSGKVVLIP
//
