ID A0A0W7XB12_9ACTN Unreviewed; 428 AA.
AC A0A0W7XB12;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KUF20001.1};
GN ORFNames=AT728_27780 {ECO:0000313|EMBL:KUF20001.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF20001.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF20001.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF20001.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF20001.1}.
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DR EMBL; LOCL01000024; KUF20001.1; -; Genomic_DNA.
DR RefSeq; WP_058845804.1; NZ_LOCL01000024.1.
DR AlphaFoldDB; A0A0W7XB12; -.
DR STRING; 1765722.AT728_27780; -.
DR OrthoDB; 5241784at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF63; SENSOR HISTIDINE KINASE DESK; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KUF20001.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 214..280
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 189..216
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 44909 MW; 893F9ADEC99BFBA0 CRC64;
MSWKNGVTCR PHGLRSRRAA RRERQADRRG LELERAGEAD AGTRPGPPNG FALLPWLLMG
LGALSHLLRG ETANPWVGGI GLLAFNSLYI GVAFRAFDKR ARESRATMAA LLAMGALTVG
LAAAYGGSWL MYFPLFGLAV GAVVRGRRLG PVGLGLSALA GAVAGFKEGW DGINIAYGTF
LSTMVTAAIL SLSEAVRDLR AAREELARRA VAEERLRFSR DQHDLLGHTL SLIVVKSEAA
RRLAPRNMDA ALTQISDIES VGRQALTEIR EAVTGYRNGT LATELDRVSD LLDAAGAAVT
VRQSGPPLDP RSEALLGWVV REAATNVVRH ARASRCDIEV TGTAEQTRLL ITDDGRGVGS
TTPGSGLKGL AERLAAAGGS LTAGPGPRGG FRVAAVLPVT DTTAPRPARA GAGTAGPARA
GAREEHSP
//
