ID A0A0W8CA52_PHYNI Unreviewed; 445 AA.
AC A0A0W8CA52;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=AP-2 complex subunit alpha {ECO:0000313|EMBL:KUF92772.1};
DE SubName: Full=Kinase 2 protein {ECO:0000313|EMBL:KUF80968.1};
GN ORFNames=AM587_10008219 {ECO:0000313|EMBL:KUF80968.1}, AM588_10004038
GN {ECO:0000313|EMBL:KUF92772.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF80968.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|Proteomes:UP000052943, ECO:0000313|Proteomes:UP000054636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943}, Race 0
RC {ECO:0000313|EMBL:KUF80968.1}, Race 1 {ECO:0000313|EMBL:KUF92772.1},
RC and race 1 {ECO:0000313|Proteomes:UP000054636};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily.
CC {ECO:0000256|RuleBase:RU000304}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF80968.1}.
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DR EMBL; LNFO01004476; KUF80968.1; -; Genomic_DNA.
DR EMBL; LNFP01000443; KUF92772.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W8CA52; -.
DR STRING; 4790.A0A0W8CA52; -.
DR EnsemblProtists; KUF80968; KUF80968; AM587_10008219.
DR EnsemblProtists; KUF92772; KUF92772; AM588_10004038.
DR OMA; CVIYDMM; -.
DR OrthoDB; 3028764at2759; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR Proteomes; UP000054636; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05123; STKc_AGC; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000961; AGC-kinase_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR017892; Pkinase_C.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR045270; STKc_AGC.
DR PANTHER; PTHR24351:SF247; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24351; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00433; Pkinase_C; 1.
DR SMART; SM00133; S_TK_X; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KUF80968.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW ECO:0000256|RuleBase:RU000304};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 109..369
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 370..443
FT /note="AGC-kinase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51285"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 138
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 445 AA; 49733 MW; FA319A7003B53C9C CRC64;
MGNKGSKGAK SLRPPIKSDS RGFKFGNYAN GGRDAGKSAP AAPSYPSNGP PPAPGQAQAQ
QQQQQQQQQQ QTEEESDLED DDSGPIEQVA IEDMDGPARP QTKVNVEDFD LLKVLGKGSF
GKVMMVRKKD TKMIYAMKTL RKAALVKRNQ LLHTKTERSI LQSIKHPYLT SLTYAFQTPD
KLYLVMDYCG GGELFFWLKK DRRFSQQKAR LFAAEIILAL QELHKHDIIY RDLKPENILL
DLEGHIRLTD FGLSKEAVTG AGATGGTKTF CGTPEYLAPE ILENKGHGKA VDWWSLGTLI
YEMLTGLPPF YDQNMQRMYD KILNAPLRFP SFMSAEAKDL LTGLLTRKVA DRLGSGPTDA
EEIKSHPFFK GIDWEAVLRK EVQPEFKPPN RLGSMDTSNF DVEFTAEKPV DSVVTTTMSE
TQRNKAQFPG FTYNADTIDE DHKGN
//
