ID A0A0W8CKX1_PHYNI Unreviewed; 1444 AA.
AC A0A0W8CKX1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 03-MAY-2023, entry version 28.
DE RecName: Full=TBC1 domain family member 23 {ECO:0000256|ARBA:ARBA00014207};
GN ORFNames=AM587_10007607 {ECO:0000313|EMBL:KUF84680.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF84680.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUF84680.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC {ECO:0000256|ARBA:ARBA00004601}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF84680.1}.
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DR EMBL; LNFO01002785; KUF84680.1; -; Genomic_DNA.
DR STRING; 4790.A0A0W8CKX1; -.
DR EnsemblProtists; KUF84680; KUF84680; AM587_10007607.
DR OMA; DMTPELY; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR039755; TBC1D23.
DR PANTHER; PTHR13297:SF5; TBC1 DOMAIN FAMILY MEMBER 23; 1.
DR PANTHER; PTHR13297; UNCHARACTERIZED; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943}.
FT DOMAIN 92..288
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 593..625
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 793..877
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 891..1002
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1212..1306
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1139..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1167..1186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1444 AA; 158721 MW; 4FDEE09C294F9F80 CRC64;
MEDPSEDDAS PSPPTPSTST QDTATSNAAV PAPNNLVQAP QSLSKVSPDS LPDSIAPKQT
TRSLLILQLE REMQKRRPDH FVIGVTCRSL GGVPSNLRSQ VWQELLGVAR TERLSLDQSI
LQVEEDLDNQ RVIAADAART RGNEPRFKQP ETVELVVKLL TYYCKCRSIQ YKQGMNEVLA
PFLLLTEQRD GAQKRVPLAE GVVFQCFYAL IDRFLPHVFV DKEFRSLQCS FQLYRLLMLY
HDPELCHYLD QHDMTPELYV TPWFMTLFAR SLPPEFVFYL WDFFLLEEDP YLLHFVAYAL
VAANREKIFD ADIAMLPQVL SSLTFSSRDE LEQVCADALA FSELTPKSYK RDLYSVCYGG
FTDAMVPFLD QLYACSSLQV YPEELVRNLM DRLATKAKEK RIPVPSAMQE EDTSLQDSLN
PLLSPATEAP LLYSSGNDAD EVTALKFIVL DCRPAEEYHK SHLSLSHHID PSIMGRPDAL
DGLMKGFSHM KGCHFCFVGP SVVSPPVLPR SSSNNAALNT IVRLARVISN DKSALEQSQK
PIEVQVEEIM SSPPTGPATL ARKQSPGEPG ALASEIGSNG ASKVHAEHES VTRLVLMFLQ
KGFKYVSHLD GGFDELEKSI KTMDTFAQEQ LLVSSPMPIP VTEHIPVPVE TSTGGFNLFA
KIGLNRSRAP SQDDFTMEVD TAARSEVSES SGLSTTITVS ESTSTSSAPN STPKEMKDIK
RKTSSAVSTL SQRLMLLKAA ARDAVSSTSS SIGLSNSSTA EVNDVEESHS TSDDGWVEVR
VKTSDTLEKN AGKITEVELQ PGPIGILFQK SRXSKIFQAV VDSVVPDSQA SATGLINTGD
LLVAVNGESL EDVPFLTVIE RVIEATRPVV LRFLTPVSSQ KDKAATVSDI PPLAPTLVSA
TRHSICITWD KLPASVASPD VARYQLQFAK QSGDEFNPWF PVAMKQEGTT AEVDSTGITD
HTNGTMVGLE PGESLVFRVR CGDGQQWGPY SLSSGSMKTL NAEKKSESGA VTPTSVGHED
VTTAVFLPGV CPEYVERGRF FYRVLLALQA RRRPDFNAEK LDIVLEKGVV IRGTERLVCP
GTNQIFVRLA FGNTDDSADQ DREYEGADGE VMLLRNGQRE ADDDADGVWA FENTPDGEVV
LERLPESATE ETGPSLQEQA KSMVQSFLNS SGISPGDNAN SNSAGSISSM VSTAASSSGG
SSVPSSSHAL VAPRILQVFA ASSSEVVVTW DPVNDVGVTK YQIQYVKDRL AAMWWTVKPD
IEADTLKYSV SGLQPNTPYV FRIRSGAEDN KWSPYNDRKS ESPSRYVNLA SWKSSSNNTD
KDFHFYHATK FQQQDEKTHR QLSNLGDREL VVTSSALVVL VVKASTPKGY ALVEEWRPLT
SLTKLEERED LDNSLVFHFK DQIEATPDSA DRTERGNQLI VVVNEAKACA KVVQEYHAKV
KLEG
//
