ID A0A0W8D0Z9_PHYNI Unreviewed; 573 AA.
AC A0A0W8D0Z9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Translation initiation factor IF-2 {ECO:0000313|EMBL:KUF90083.1};
GN ORFNames=AM587_10017006 {ECO:0000313|EMBL:KUF90083.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF90083.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUF90083.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF90083.1}.
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DR EMBL; LNFO01001581; KUF90083.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W8D0Z9; -.
DR STRING; 4790.A0A0W8D0Z9; -.
DR EnsemblProtists; KUF90083; KUF90083; AM587_10017006.
DR OMA; ESIGCIE; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF20; TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF11987; IF-2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KUF90083.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943}.
FT DOMAIN 125..298
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 420..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2..29
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 420..435
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..460
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 62974 MW; 7BD2C901B7831A85 CRC64;
MARIAKLEAM TQERERARQE QRRRVLEARN QPPVIPAFIR VRDLAKALRQ PLDKVLKHTV
IKANRRFNLK TKNHPPAEFR SVKHIVLPFR VAHEVAESFG IQVAYDDVEP ELLNAVSCDE
EFLGRRQPVI AVMGHVDHGK TTLMDTLRKQ MKAGLRQIAP YEKHGITQKI NVCEAALTPD
VKATFLDTPG HFHFFRMRSS AAQVADAVLL IVAADEGVLL QTEESIGAIE EAGLPAVICI
NKVDLLGEDG DEQVDKIVDE LRSFVALQDS PVLTISGKTG AGLDDLKHTV WELVTGLADN
NRLDALVGSE THAEGLVLES VALKGRGTVL RVLIKNGELA AKQHFVAGMI HGVVRNIRDA
EGRDVKRALP GTVVDITYSN KSKNVDAPNE HGFFVLPEAR AKQVIEQREL AMEFNDCLLP
DEGGEHARPD AEYTSTETDG DDEGVSDAET LNDEAEEEDD DVIDENDLIE TKSIIVKADG
AGSLTSIQDT VDEMAGISTV RLGIGNISTK DIDVAINGKC PIFGFNVKLR NREAKLATER
GVRVILRSTV HELIEEITAF EQTDSEDDDA TSG
//
