ID A0A0W8DPE6_PHYNI Unreviewed; 958 AA.
AC A0A0W8DPE6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Exocyst complex component 8 {ECO:0000256|ARBA:ARBA00017509};
GN ORFNames=AM587_10014221 {ECO:0000313|EMBL:KUF98227.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF98227.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUF98227.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC exocytic vesicles with fusion sites on the plasma membrane.
CC {ECO:0000256|ARBA:ARBA00002660}.
CC -!- SUBCELLULAR LOCATION: Cell projection, growth cone
CC {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}.
CC -!- SIMILARITY: Belongs to the EXO84 family.
CC {ECO:0000256|ARBA:ARBA00007210}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF98227.1}.
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DR EMBL; LNFO01000892; KUF98227.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W8DPE6; -.
DR STRING; 4790.A0A0W8DPE6; -.
DR EnsemblProtists; KUF98227; KUF98227; AM587_10014221.
DR OMA; ANSFATM; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0000145; C:exocyst; IEA:InterPro.
DR GO; GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00821; PH; 1.
DR Gene3D; 1.20.58.1220; Exo84p, C-terminal helical domain; 1.
DR Gene3D; 1.20.58.1210; Exo84p, N-terminal helical domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR033961; Exo84.
DR InterPro; IPR032403; Exo84_C.
DR InterPro; IPR042561; Exo84_C_1.
DR InterPro; IPR042560; Exo84_C_2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21426; EXOCYST COMPLEX COMPONENT 8; 1.
DR PANTHER; PTHR21426:SF12; EXOCYST COMPLEX COMPONENT 8; 1.
DR Pfam; PF16528; Exo84_C; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF08700; VPS51_Exo84_N; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 10..104
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 116..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 958 AA; 108830 MW; 9B10CD4065D4ACA6 CRC64;
MVSGPEALRI AIRDGILERK RRAGYWTKRQ FVLTPTHLMY FETMEAKEPV NSFATMEIMA
VQKSISDPQQ RMFTLVLFKK KKEYRARSTE DRDAWVAALE SVSGMKGTGV VTIPAKKDEV
LTRDEPPVGD DREKESRGER ESGSNIQDVK DVDLRALCEQ MKKSFSWQIQ ISKSFSSKDV
AEFVKKTLPH LSTAQIQEVG QGFIDLKLII PLKSHIFDAT DPGRFKFVET TAPKQPKNHL
SMGGPSIANL MGNQQFNARK YAEDFLRKHS QLKIDSHCKK LVAQKENTIE DLKEEISANY
TSFIRAADEI KTMENSVSQL KALVLECRRT MHTLKGVALE PPPEKVTQLD FKAVDKKAEE
RKQSMALDEF IRDLEVYLYE RNYEQFTQHI LEYKRKETQG IESATEAQQA KIDELRHLLV
EKLVDEFNAS LQTSERMHKK ENHLEFLIQL GETQLATEMC LQNYSVRIAL QLRHVPSYGN
ALNYVINFSR TFFTSLLVCY EDFEHSFRGQ KSSHFISLTV WISSQLEHFA SEVTYHIFPD
DPSASSSRSS STVSGPSLPA SCVAIDVSEF KSVAKYVSSA LRYVFYGSRQ LELAGLPTAH
YLAPHLARGL VSFFTSYCVA IKNTVREEIK RERWEMTSRM IRDPENKAER EIVLTQSARS
FYTLVQQFLR DVQRVMNPSC ATSNLAEVHE VVVWEADELL VHYSFEELQY LESSKLSSSL
RPKHIVGILT NAAYIQDDCA ARSTNILQEY LPKVALQNRE VEAKNSNLWE KLAAIGVKRC
AQSLMNMSFS WQDMELADET LPDVSSSPDS STTSSLFAGV VAKELADIMT NNQLNKAVRN
GSLASDGKDV GKQVSFAGMV LDALFREMLE DEPWWQNFNG KGGAGRKRLG YGGVNRFLTE
IYALRDLIPT SKGVELTSKI DTKMMEIYQQ LYPGRKDVRA PAEWTQTYAK RCIAAASR
//
