ID A0A0W8DQN0_PHYNI Unreviewed; 681 AA.
AC A0A0W8DQN0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 08-NOV-2023, entry version 36.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
DE AltName: Full=Diadenosine tetraphosphate synthetase {ECO:0000256|ARBA:ARBA00030057};
GN ORFNames=AM587_10014670 {ECO:0000313|EMBL:KUF79825.1}, AM587_10015177
GN {ECO:0000313|EMBL:KUF85354.1}, AM588_10010511
GN {ECO:0000313|EMBL:KUF98660.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF98660.1, ECO:0000313|Proteomes:UP000054636};
RN [1] {ECO:0000313|Proteomes:UP000052943, ECO:0000313|Proteomes:UP000054636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943}, Race 0
RC {ECO:0000313|EMBL:KUF79825.1}, Race 1 {ECO:0000313|EMBL:KUF98660.1},
RC and race 1 {ECO:0000313|Proteomes:UP000054636};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF98660.1}.
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DR EMBL; LNFO01004693; KUF79825.1; -; Genomic_DNA.
DR EMBL; LNFO01002552; KUF85354.1; -; Genomic_DNA.
DR EMBL; LNFP01000060; KUF98660.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W8DQN0; -.
DR STRING; 4790.A0A0W8DQN0; -.
DR EnsemblProtists; KUF79825; KUF79825; AM587_10014670.
DR EnsemblProtists; KUF85354; KUF85354; AM587_10015177.
DR EnsemblProtists; KUF98660; KUF98660; AM588_10010511.
DR OrthoDB; 546660at2759; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR Proteomes; UP000054636; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00774; GlyRS-like_core; 1.
DR CDD; cd00858; GlyRS_anticodon; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.30.720.200; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR Gene3D; 1.10.287.10; S15/NS1, RNA-binding; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR InterPro; IPR009068; uS15_NS1_RNA-bd_sf.
DR InterPro; IPR000738; WHEP-TRS_dom.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR Pfam; PF00458; WHEP-TRS; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SMART; SM00991; WHEP-TRS; 1.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF47060; S15/NS1 RNA-binding domain; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
DR PROSITE; PS00762; WHEP_TRS_1; 1.
DR PROSITE; PS51185; WHEP_TRS_2; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KUF79825.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 8..64
FT /note="WHEP-TRS"
FT /evidence="ECO:0000259|PROSITE:PS51185"
FT DOMAIN 244..562
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT COILED 9..56
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 681 AA; 76001 MW; C4F9B8A3B673FCED CRC64;
MSSTPVVDLD ALRASVTRQG AQVRELKQKG AAAEDVKAAV DELKKLKLEL ETQTALQGPA
EDGLSKSDKK ALDDLLLRKM FVVPSFEIYG GVGGFYDFGP PACALKSNLL QFWRRHFVFA
DKLLEVECTN LMPEVVLKTS GHVDRFTDLM VKCTKSGECY RADKLLEDHV ENFLDKHPDL
SKEEREKHEL HATMAESYSP EEIHAVFQEY GIKAPGTGAD LSFPIPFNLM FKCAIGPEGG
LVGYLRPETA QGIFLNFRRL LEYNAGKVPF GCAQIGSAFR NEISPRAGLL RVREFQQAEI
EFFVNPKDKS HAKFSTIKDL ELPLLTKTNQ LTHGKAVQMT CGAAVEQGII ANESLAYYLA
RTYKFCKAIG IDMERLRFRQ HLNTEMAHYA TDCWDLEIKL SSGWVECAGH ADRSCYDLSV
HAKKSKVEMV GTHKFDKPEK RQIVEIKPNK GKMGRTFKAD VATILEALEA LKDDVPRAQA
FEDELASKGE ATLGPLCDGK QFTLQRDMVA IKVVEKMVSE EKFVPSVIEP SFGIGRILTA
VFEHNFYTRE GDEKRGVMSF SPLIAPIKVS VLPLSNNPAF EPFATELENV FVEEGLECKV
DTSSVAIGRK YARADELGIP FNVTIDFDTV KDRVVTLRER DSTAQVRIPM DAIGAEVNKL
VKGSTTWEKM LEQYPKVTAA E
//
