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Database: UniProt
Entry: A0A0W8JGR2_9VIBR
LinkDB: A0A0W8JGR2_9VIBR
Original site: A0A0W8JGR2_9VIBR 
ID   A0A0W8JGR2_9VIBR        Unreviewed;       352 AA.
AC   A0A0W8JGR2;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   08-MAY-2019, entry version 14.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=VRK_15260 {ECO:0000313|EMBL:KUI99442.1};
OS   Vibrio sp. MEBiC08052.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=1761910 {ECO:0000313|EMBL:KUI99442.1, ECO:0000313|Proteomes:UP000054473};
RN   [1] {ECO:0000313|EMBL:KUI99442.1, ECO:0000313|Proteomes:UP000054473}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MEBiC08052 {ECO:0000313|EMBL:KUI99442.1,
RC   ECO:0000313|Proteomes:UP000054473};
RA   Kim Y.J., Lee J.-H., Kwon K.K.;
RT   "Genome sequence of Vibrio sp. MEBiC08052.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KUI99442.1}.
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DR   EMBL; LQIY01000009; KUI99442.1; -; Genomic_DNA.
DR   RefSeq; WP_059120739.1; NZ_KQ947475.1.
DR   EnsemblBacteria; KUI99442; KUI99442; VRK_15260.
DR   PATRIC; fig|1761910.3.peg.1538; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000054473; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054473};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:KUI99442.1}.
FT   DOMAIN       42    336       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   352 AA;  39160 MW;  CAC99C6D3D37BED0 CRC64;
     MKTDELRTEP LGHMPTPEQL RIQSPVSASV GQHISQSRQE IEAILHGRDH RLLVITGPCS
     IHDPVAALDY AKRLNILRER YADNLLIVMR TYFEKPRTVV GWKGLITDPY LDGRYALEEG
     LSKAREVLLA INQLGLPTAT EFLDMITGQY IADLISWGAI GARTTESQIH REMASALSCP
     VGFKNATNGN VKVAVDAIRA AKASHYFYSP DRQGRMTVYR TSGNPDGHVI LRGGENGPNF
     DSKSVQQACA QLESHHLSPR VVIDFSHANC QKQHKRQLSV AEDICRQIRR GSDQIAGIMA
     ESFIKEGHQP IAALDQLTYG MSITDPCLSW SDTELMITEL NAAVHDRNND KR
//
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