ID A0A0W8JGZ6_9VIBR Unreviewed; 453 AA.
AC A0A0W8JGZ6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=MotA/TolQ/ExbB proton channel domain-containing protein {ECO:0000259|Pfam:PF01618};
GN ORFNames=VRK_16040 {ECO:0000313|EMBL:KUI99520.1};
OS Vibrio sp. MEBiC08052.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=1761910 {ECO:0000313|EMBL:KUI99520.1, ECO:0000313|Proteomes:UP000054473};
RN [1] {ECO:0000313|EMBL:KUI99520.1, ECO:0000313|Proteomes:UP000054473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MEBiC08052 {ECO:0000313|EMBL:KUI99520.1,
RC ECO:0000313|Proteomes:UP000054473};
RA Kim Y.J., Lee J.-H., Kwon K.K.;
RT "Genome sequence of Vibrio sp. MEBiC08052.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU004057}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004057}.
CC -!- SIMILARITY: Belongs to the exbB/tolQ family.
CC {ECO:0000256|RuleBase:RU004057}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUI99520.1}.
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DR EMBL; LQIY01000009; KUI99520.1; -; Genomic_DNA.
DR RefSeq; WP_059120806.1; NZ_KQ947475.1.
DR AlphaFoldDB; A0A0W8JGZ6; -.
DR STRING; 1761910.VRK_16040; -.
DR PATRIC; fig|1761910.3.peg.1613; -.
DR OrthoDB; 4045at2; -.
DR Proteomes; UP000054473; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR017270; MotA/TolQ/ExbB-rel.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR PANTHER; PTHR30625; PROTEIN TOLQ; 1.
DR PANTHER; PTHR30625:SF11; TOLQ-TYPE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF01618; MotA_ExbB; 1.
DR PIRSF; PIRSF037714; TolR; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|RuleBase:RU004057};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU004057}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..453
FT /note="MotA/TolQ/ExbB proton channel domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006944613"
FT TRANSMEM 270..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 321..428
FT /note="MotA/TolQ/ExbB proton channel"
FT /evidence="ECO:0000259|Pfam:PF01618"
FT REGION 29..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 53..80
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 38..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 48942 MW; 66C00B728FA557F3 CRC64;
MKLKVCLSLC LLGLTTPTLA DTNQKPLVNQ AQAAQQQERQ HNREREGAFQ QTEQTLREEA
ERLQKNKAAL QKEIDSLTSQ FSKNESALAK QEEKLRLETG SLGEIFGVVR QNAKTLKSDL
SHSITQIDRQ TYTPVVDDIV AAKSLPSLKQ LNGLWQSMNE QIRASGEVAS VNIPYVDEAG
IKKTEAAARL GSFGLITDQG YMNWDHNKQV AIPYLKQPDD GPTLGSIAPL LAGQTQPLIV
DPSKGTLLAQ LANAPTMLDR LKAGGVVGNI ILGLLAIGLI IGLFRGISLA VIKQKIKAQL
KTPERHGDNP LGRVLSVYDK EKHRSVEALE LRLLEVVVDE QSHLEKGLSM LKLLAALAPM
LGLLGTVTGM IETFQVITQF GNGDPKVMAG GISMALITTV LGLVAAMPML LAHNILSSQA
ESIRTILEKQ GIGLVAAQAE NDQAAKDDVE QAA
//
