ID A0A0X1SWY2_PSEAA Unreviewed; 249 AA.
AC A0A0X1SWY2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Sulfate transporter CysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN Name=cysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN ORFNames=AWM79_03315 {ECO:0000313|EMBL:AMB84382.1};
OS Pseudomonas agarici.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=46677 {ECO:0000313|EMBL:AMB84382.1, ECO:0000313|Proteomes:UP000063229};
RN [1] {ECO:0000313|EMBL:AMB84382.1, ECO:0000313|Proteomes:UP000063229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2472 {ECO:0000313|EMBL:AMB84382.1,
RC ECO:0000313|Proteomes:UP000063229};
RA McClelland M., Jain A., Saraogi P., Mendelson R., Westerman R.,
RA SanMiguel P., Csonka L.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: High affinity, high specificity proton-dependent sulfate
CC transporter, which mediates sulfate uptake. Provides the sulfur source
CC for the cysteine synthesis pathway. {ECO:0000256|HAMAP-Rule:MF_00468}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_00468}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
CC -!- SIMILARITY: Belongs to the CysZ family. {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
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DR EMBL; CP014135; AMB84382.1; -; Genomic_DNA.
DR RefSeq; WP_017130694.1; NZ_JACAQG010000029.1.
DR AlphaFoldDB; A0A0X1SWY2; -.
DR STRING; 46677.AWM79_03315; -.
DR OrthoDB; 5292355at2; -.
DR Proteomes; UP000063229; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0000103; P:sulfate assimilation; IEA:InterPro.
DR HAMAP; MF_00468; CysZ; 1.
DR InterPro; IPR022985; Sulfate_CysZ.
DR PANTHER; PTHR37468; SULFATE TRANSPORTER CYSZ; 1.
DR PANTHER; PTHR37468:SF1; SULFATE TRANSPORTER CYSZ; 1.
DR Pfam; PF07264; EI24; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_00468}; Cysteine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00468};
KW Reference proteome {ECO:0000313|Proteomes:UP000063229};
KW Sulfate transport {ECO:0000256|ARBA:ARBA00023032, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00468}.
FT TRANSMEM 26..47
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 67..96
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 147..180
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 211..238
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
SQ SEQUENCE 249 AA; 28334 MW; 3D79A8214E8640BA CRC64;
MPAPVMSGPQ YLREGLKLVL SPGLRLFVLL PLLINLVLFV GLIYFAGHQF SLWVDHLMPT
LPHWLSFLNY ILWPLFVALV ILMVFFSFTL LANIIASPFN GFLAEKVEVV VRGTDDFPAF
SWTELLAMVP RTLAREMRKL GYFLPRALGL FVLSFIPVVN IIAAPLWLLF GVWMMAIQYI
DYPADNHKLG WNEMLAWLRQ KRWQSMSFGG IVYLVLLIPV VNILMMPAAV AGATLFWVRE
RGNEALAQP
//
