ID A0A0X1SZ01_PSEAA Unreviewed; 356 AA.
AC A0A0X1SZ01;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:AMB85072.1};
GN ORFNames=AWM79_07015 {ECO:0000313|EMBL:AMB85072.1};
OS Pseudomonas agarici.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=46677 {ECO:0000313|EMBL:AMB85072.1, ECO:0000313|Proteomes:UP000063229};
RN [1] {ECO:0000313|EMBL:AMB85072.1, ECO:0000313|Proteomes:UP000063229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2472 {ECO:0000313|EMBL:AMB85072.1,
RC ECO:0000313|Proteomes:UP000063229};
RA McClelland M., Jain A., Saraogi P., Mendelson R., Westerman R.,
RA SanMiguel P., Csonka L.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP014135; AMB85072.1; -; Genomic_DNA.
DR RefSeq; WP_060782485.1; NZ_CP014135.1.
DR AlphaFoldDB; A0A0X1SZ01; -.
DR STRING; 46677.AWM79_07015; -.
DR Proteomes; UP000063229; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000063229}.
FT DOMAIN 243..337
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 217..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 39389 MW; DDB0D6E22129F209 CRC64;
MKTERIAVTL LTGFLGAGKT TLLNRILTGD HGRRYAVIVN EFGEIGIDAS LIVSADEELF
EMNNGCLCCT VRGDLIRTLH GLLERQSNFD AIIIETTGLA DPGPVAQTFF IDPVLQAKLS
LDSITTVVDA KHILQTLESS PEAEEQIAFA DQIILNKVAL VSEADLPCIE ARLRRINPFS
PIHRANRADV PLHAILGIGS FDLERITALE SDFLDPHHHG QANHAHDEHC DHHPHDHSHD
RTIQSLVLES ERPMDAEKLS NWLTTYLTEN GQDILRAKGI IDAAGESRKL VFQAVHMMLE
GDFQRPWAPS EKRHSQLVFI GRHLDPAQLR AGMEACAASP VMELLDKNGY GGIHDE
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