ID A0A0X1T5X5_PSEAA Unreviewed; 305 AA.
AC A0A0X1T5X5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:AMB87514.1};
GN ORFNames=AWM79_20345 {ECO:0000313|EMBL:AMB87514.1};
OS Pseudomonas agarici.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=46677 {ECO:0000313|EMBL:AMB87514.1, ECO:0000313|Proteomes:UP000063229};
RN [1] {ECO:0000313|EMBL:AMB87514.1, ECO:0000313|Proteomes:UP000063229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2472 {ECO:0000313|EMBL:AMB87514.1,
RC ECO:0000313|Proteomes:UP000063229};
RA McClelland M., Jain A., Saraogi P., Mendelson R., Westerman R.,
RA SanMiguel P., Csonka L.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP014135; AMB87514.1; -; Genomic_DNA.
DR RefSeq; WP_060783641.1; NZ_CP014135.1.
DR AlphaFoldDB; A0A0X1T5X5; -.
DR STRING; 46677.AWM79_20345; -.
DR Proteomes; UP000063229; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000063229}.
FT ACT_SITE 138
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 166
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 208
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 305 AA; 33142 MW; D1028AE06C38E8BE CRC64;
MNKRINWSGV FPAVTTQFND DFSINLEKTH QVISNVIRDG VSGLVVCGSV GENTSLSTEE
KIAVTEVAVD AAKGRVPVIC GVAEFTSVQA AKVANAVRQV GIDGVMLMPA LVYGSKPFET
AEHYRYVAKH TDLALMVYNN PPIYKNDVTP DILISLADCD NVVCFKDSSG DTRRFIDVRN
EVGDRFVLFA GLDDVVLESI AVGAEGWVSG MSNVFPKEGE TIFRLAKAGR FAEALPIYEW
LMPILHLDAR ADLVQCIKLC EAIAGRGSAL TRPPRLALPE ADRLFVEQIM AKAMANRPAL
PDVGL
//
