ID   A0A0X3BPJ0_9EURY        Unreviewed;       730 AA.
AC   A0A0X3BPJ0;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=HQQ74_04455 {ECO:0000313|EMBL:NQS77949.1}, MMAB1_2873
GN   {ECO:0000313|EMBL:CVK34086.1};
OS   Methanoculleus bourgensis.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX   NCBI_TaxID=83986 {ECO:0000313|EMBL:CVK34086.1, ECO:0000313|Proteomes:UP000069850};
RN   [1] {ECO:0000313|EMBL:CVK34086.1, ECO:0000313|Proteomes:UP000069850}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Methanoculleus sp MAB1 {ECO:0000313|EMBL:CVK34086.1};
RA   Manzoor S.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:NQS77949.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MAG54 {ECO:0000313|EMBL:NQS77949.1};
RA   Singh A., Schnurer A., Westerholm M.;
RT   "The first insight into the ecology of ammonia-tolerant syntrophic
RT   propionate oxidizing bacteria.";
RL   Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; LT158599; CVK34086.1; -; Genomic_DNA.
DR   EMBL; JABMJE010000043; NQS77949.1; -; Genomic_DNA.
DR   RefSeq; WP_062265311.1; NZ_LT158599.1.
DR   AlphaFoldDB; A0A0X3BPJ0; -.
DR   GeneID; 27138400; -.
DR   KEGG; mema:MMAB1_2873; -.
DR   OrthoDB; 116705at2157; -.
DR   Proteomes; UP000069850; Chromosome chrI.
DR   Proteomes; UP000737555; Unassembled WGS sequence.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 4.
DR   Gene3D; 3.30.450.20; PAS domain; 4.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 3.
DR   PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 4.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 3.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CVK34086.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000069850};
KW   Transferase {ECO:0000313|EMBL:CVK34086.1}.
FT   DOMAIN          30..91
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          94..146
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          282..350
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          398..468
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          471..521
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   730 AA;  82885 MW;  59D260090273BB73 CRC64;
     MDTIKESPHT KTPAPRDPDE TGAIPPAVNE SIPYGIWIAG PEGDILHISD SFLDLIGMTI
     DECRQPEWLR LLHPEDMGAV LADRARCIAS GECWNREFRV LGTDGEYHTI QSRGMPIRND
     EGEVLLWAGV NLDGQQKLQP RAPGRERQAR RMETLSRISG VIAQGEGNLQ EICRQVVAWM
     PDGFRHPELI SARIIIGGAV FMTGDDNHRR IVAALPAERG VAGYLEVEYQ GPLPRGTRDL
     FKPQERNFVH TVAVMIGNVI GREETKAALK SLERQHRLLS DQILESIILM ETVRDNFGEP
     VDYRCIAINS RAEEEIGYGR DEVIGKTFFE FFPGTSPELR AMLCRVAKTG TPEHGEAHCQ
     KLDGYYEVRA YRPQCNQLAL IVNDITVQKK TEEALRESEE KYRMLVETAR DAIIVHDTKT
     FLYANPAAGA LFGAERPEDL VGMNFIDRVH PDNRDQIRAR MSEVISGEIP LPQEVQILRL
     DGSAVPVESA TSPVAYSGKK MVQVTMRDIS RRKRYEAALR RNGERFRRLF NQSPIGIEYY
     NPEGRLLHIN RASLAIFGIP GRRDVIGYNL FEDPSTPAWA WERFRRGDEA HYTIPVDLDL
     ARRDGTYPTT RTGTIYVDVH ASPVHDRKTG VLKGILVQIQ DVTDRVRMED QRQQAFTQIE
     QNIEQFAILA DHIRLPLQVI LGTADLIDED EASERIREQV ERINSIVRQL DKGWIASREI
     REFLRRNELL
//