ID A0A0X3RQ53_9ACTN Unreviewed; 283 AA.
AC A0A0X3RQ53;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Phosphogluconate dehydrogenase {ECO:0000313|EMBL:KUJ33748.1};
GN ORFNames=ADL25_43970 {ECO:0000313|EMBL:KUJ33748.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ33748.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ33748.1}.
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DR EMBL; LMWH01000302; KUJ33748.1; -; Genomic_DNA.
DR RefSeq; WP_059133581.1; NZ_LMWH01000302.1.
DR AlphaFoldDB; A0A0X3RQ53; -.
DR OrthoDB; 1271986at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR015814; Pgluconate_DH_NAD-bd_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF09130; DUF1932; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054048}.
FT DOMAIN 5..151
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 189..257
FT /note="Phosphogluconate dehydrogenase NAD-binding putative
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09130"
FT ACT_SITE 168
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 283 AA; 29462 MW; 52E4A9F55ED78413 CRC64;
MTVVGVLHPG SMGAAVAAQA RLNGAEVLWC PTGRSLATAE RAQRSELTAV GSLGELTERA
DVILSICPPA YAEDVAVEVS AHPFTGIYVD GNAISPASMA RISTTMGRTG ATVVDSSVIG
SPPSDSKSAR LYLSGPADAL TPVASLFAGT AVQAHTLPGG IGRASALKLS YSSYQKASRI
LAAVSYALAE DYGVEEELLD IAQGRTTSYL AETAYIPKVA ARAWRWGPEM LEVAAALREV
GLPADLAEAS AVVMSRWDGH RDSSMSISDA LEQLHHGTDD EPH
//
