ID A0A0X3RUE1_9ACTN Unreviewed; 409 AA.
AC A0A0X3RUE1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KUJ35248.1};
GN ORFNames=ADL25_38045 {ECO:0000313|EMBL:KUJ35248.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ35248.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ35248.1}.
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DR EMBL; LMWH01000276; KUJ35248.1; -; Genomic_DNA.
DR RefSeq; WP_059132513.1; NZ_LMWH01000276.1.
DR AlphaFoldDB; A0A0X3RUE1; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KUJ35248.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054048};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 303..399
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
FT REGION 346..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 169..196
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 409 AA; 43290 MW; 794ECD8D68CA13F5 CRC64;
MSTLERTRDG LRAHPLALDA ALAFGVLVCM VVGSFVDPHG QDGPTWGART PAAPSLTLLV
LSAAALVFRR RRPVTVLAVT AALSLVELVT ADPRVPVAMS AVVALYTVAA TTDRPTTWRV
GLLTMTALTG AAMLAGTVPW YAQENLGIFA WTGMAAAAGD AVRSRRAFVH AIRERAERAE
RTREEEARRR VAEERLRIAR DLHDVVAHHI ALVNVQAGVA AHVMDRRPDQ AKEALAHVRE
ASRSALNELR ATVGLLRQSG DPEAPTEPAP GLARLDELAD TFRNAGLPVE VARADHGTAL
PAAVDLAAYR VIQEALTNVQ KHAGQRAKAE VSVVRVGSAV EITILDDGTG EDPGPEDDGH
GGHGLLGMRE RVTALGGTLA AGPRYGGGFR VHAILPVRNR ATTTAGETV
//
