ID A0A0X3RWB5_9ACTN Unreviewed; 440 AA.
AC A0A0X3RWB5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=3-carboxy-cis,cis-muconate cycloisomerase {ECO:0000313|EMBL:KUJ36002.1};
GN ORFNames=ADL25_34300 {ECO:0000313|EMBL:KUJ36002.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ36002.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II fumarase/aspartase family.
CC {ECO:0000256|ARBA:ARBA00034772}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ36002.1}.
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DR EMBL; LMWH01000259; KUJ36002.1; -; Genomic_DNA.
DR RefSeq; WP_059131807.1; NZ_LMWH01000259.1.
DR AlphaFoldDB; A0A0X3RWB5; -.
DR OrthoDB; 9768878at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR GO; GO:0019619; P:3,4-dihydroxybenzoate catabolic process; IEA:InterPro.
DR CDD; cd01597; pCLME; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR019468; AdenyloSucc_lyase_C.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR InterPro; IPR012789; Protocat_PcaB-like.
DR NCBIfam; TIGR02426; protocat_pcaB; 1.
DR PANTHER; PTHR43172; ADENYLOSUCCINATE LYASE; 1.
DR PANTHER; PTHR43172:SF2; ADENYLOSUCCINATE LYASE C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10397; ADSL_C; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SMART; SM00998; ADSL_C; 1.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:KUJ36002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054048}.
FT DOMAIN 362..437
FT /note="Adenylosuccinate lyase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00998"
FT REGION 416..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 46017 MW; 6A0DA5C2A44CA4E4 CRC64;
MTSDTGLLAP GWVGSPAADT TSDTAWLRAM LDAEVALTRA LASSGLAPAA AAAAVAEAAR
RNRFDVCSIA RRARAGGNPV IPLVADLTEA VGAEHGPYVH RGATSQDILD TATMLVAVRT
LDPVLADLER TQTALAELAA RHRDTVMPGR TLTQHAVPTT FGLKAAGWRS LVLDARDRVR
TVRDGLPAQL GGAAGTLAAF TAYGADDPRA LTAAYAQELR LADPVLPWHS LRTPIADLAG
GLAFTAGALG KLAADVLTLG RTEIAEVGEA AGGGSSAMPH KANPVRATLI AAAARRAPQL
AATLYGSLTA EDERPAGAWH AEWEPLRDLL RLVGGAARDG AELAEGLQVD EESMRRHLFL
THGLIVSERL AAELTPLLGR ARARELLDEV ARRARTESRS LAELLSADAE LKEIDLEGPT
DPAQYTGSAG SLTDRALERS
//
