ID A0A0X3RZS8_9ACTN Unreviewed; 447 AA.
AC A0A0X3RZS8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ADL25_38165 {ECO:0000313|EMBL:KUJ35061.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ35061.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ35061.1}.
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DR EMBL; LMWH01000277; KUJ35061.1; -; Genomic_DNA.
DR RefSeq; WP_059132521.1; NZ_LMWH01000277.1.
DR AlphaFoldDB; A0A0X3RZS8; -.
DR OrthoDB; 9805533at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR PANTHER; PTHR11780:SF10; NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11780; NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000054048};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 64..224
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit FMN-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF01512"
FT DOMAIN 249..283
FT /note="Soluble ligand binding"
FT /evidence="ECO:0000259|Pfam:PF10531"
FT DOMAIN 336..418
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|Pfam:PF10589"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 47137 MW; DB95373AF34850E5 CRC64;
MNREREADPA LRLGEQATGP HGSRLLSGWF TTGARAGLTE HLARYGPPPL PQTGRPATAL
IRAVDEAGLT GRGGAAFPTG RKLRTVAEAR GTAVVIANGM ESEAASRKDS TLLDLAPHLV
LDGASLAAAA VGADEIHLCL ARTRTTQFRD LDVAVAERYR AGLDPVPIRL HGLPHHYVSS
EETSLVNWLN GGQARPLPTP PRPFEKGVDG RPTLIDNVET LAHLALIVRY GPHWFRSAGR
PDAPGTTLVT LSGAVRTPGV YEIPLGTTLA AMVQTAGGAT RPLRALLVGG YFGSWLLADQ
VQNLPYTKPD LATAGAGPGA GVLFALPDNG CGLSETARVL DYLARQSAQQ CGPCRFGLPA
VAGDFATLAW GRPDAALLAR LRQRAGLLAG RGACRHPDGA SRLAATALEV FVDEVHRHLT
HRRCPGARTA PLLHVPDAPG PEQEGWQ
//
