ID A0A0X3S5Y0_9ACTN Unreviewed; 352 AA.
AC A0A0X3S5Y0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Stilbene synthase {ECO:0000313|EMBL:KUJ38576.1};
GN ORFNames=ADL25_23455 {ECO:0000313|EMBL:KUJ38576.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ38576.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ38576.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMWH01000233; KUJ38576.1; -; Genomic_DNA.
DR RefSeq; WP_059129778.1; NZ_LMWH01000233.1.
DR AlphaFoldDB; A0A0X3S5Y0; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054048}.
FT DOMAIN 6..201
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 217..351
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 139
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 352 AA; 37188 MW; E6DEB8C199EBCCE4 CRC64;
MTRIAAVHGA LAPHRHSQSE ITDMVARTCL PEDGDRRVLD RLHRSTRVGS RHMTLPLERY
GTLDGFGAAN NVFITAATDL GAKAVRAVLR TAGLTAADVD LLIFTSVTGI ATPSIDARLV
GRLGLRPDVH RLPLFGLGCA GGAAGLARMH DYLLGRPGHV AVLLSVELCS LTFQRDDASM
ANLVATGLFG DGAAAVIAYG ADHPNATLGP TIVDTRSHLY PDTGHVMGWD IRSSGFQVVL
DPGLPDLVRR YLADDVEGFL GDHGLKPKDV TAWVCHPGGP KVLGAVAEAL DLSADALDVT
WRHLADVGNL SSSSVLHVLS DTLAERRPPP GTPGLLLAMG PGFACELVLL RW
//
