ID A0A0X3SB28_9ACTN Unreviewed; 426 AA.
AC A0A0X3SB28;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Beta-ACP synthase {ECO:0000313|EMBL:KUJ38045.1};
GN ORFNames=ADL25_26395 {ECO:0000313|EMBL:KUJ38045.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ38045.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ38045.1}.
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DR EMBL; LMWH01000240; KUJ38045.1; -; Genomic_DNA.
DR RefSeq; WP_059130314.1; NZ_LMWH01000240.1.
DR AlphaFoldDB; A0A0X3SB28; -.
DR OrthoDB; 9808669at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000054048};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 6..420
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 426 AA; 44976 MW; 545F52D42796C0A6 CRC64;
MSGPHARRVV ITGIGVTAPG GVGVKNFWSL LSDGRTATRR ISFFDASPFR SQIAAEVDFD
AELLGLGAQE IRRMDRAAQF AVVTAREAVE DSGLDLHSLD PHRTGVTIGS AVGATMGLDQ
EYRTVSDSGR LDLVDHEYAV PHLYNYLVPS SFAAEVAWAV GAEGPTTVVS TGCTSGLDAV
GYATELIREG SADVMVAGAA DAPISPITVA CFDAIKATTP RNDDPEHASR PFDGTRNGFV
LGEGSAVFVL EELSSARRRG AHVYAEVAGY ATRSNAFHMT GLRPDGREMA EAIRIALDEA
RLGPEAVDYV NAHGSGTKQN DRHETAAFKR SLGEHAYGVP VSSIKSMVGH SLGAIGSIEI
AASALAMEHG VVPPTANLHT ADPECDLDYV PLTARDWRTD VVLSVGSGFG GFQSAMVLAR
PDRRDA
//
