ID A0A0X3T8D5_9GAMM Unreviewed; 502 AA.
AC A0A0X3T8D5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=RNA polymerase sigma-54 factor {ECO:0000256|ARBA:ARBA00019942, ECO:0000256|PIRNR:PIRNR000774};
GN ORFNames=AVO41_06240 {ECO:0000313|EMBL:KUJ72035.1};
OS Thiomicrospira sp. WB1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Thiomicrospira.
OX NCBI_TaxID=1685380 {ECO:0000313|EMBL:KUJ72035.1, ECO:0000313|Proteomes:UP000053531};
RN [1] {ECO:0000313|EMBL:KUJ72035.1, ECO:0000313|Proteomes:UP000053531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WB1 {ECO:0000313|EMBL:KUJ72035.1,
RC ECO:0000313|Proteomes:UP000053531};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|PIRNR:PIRNR000774}.
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798, ECO:0000256|PIRNR:PIRNR000774}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ72035.1}.
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DR EMBL; LQBN01000002; KUJ72035.1; -; Genomic_DNA.
DR RefSeq; WP_068584310.1; NZ_LQBN01000002.1.
DR AlphaFoldDB; A0A0X3T8D5; -.
DR STRING; 1685380.AVO41_06240; -.
DR OrthoDB; 9814402at2; -.
DR Proteomes; UP000053531; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000774};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Reference proteome {ECO:0000313|Proteomes:UP000053531};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000774}.
FT DOMAIN 122..324
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 339..497
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
FT REGION 60..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 57518 MW; C1359BD23ED1816A CRC64;
MALMPGLQLN MGQQLKLTPQ LQQSIKILQY SALEVQQTIA TTLETNFMLE LDDEFVEEEL
ADEPRDEASD EQTHADEKEI DLESADKLDD DMQVDCEWEE VYTDIPVATR SASLDSEYTA
PENYTAAELS LAEKLYWQAD IYPWPNPDNQ EVPDQAVIAS YLIDEIDDEG YLKTPLEQIE
AAIKKNEPEL AISVEQLEQV LAVIWEFEPT GVGARDLSEC LLLQLKPLKQ TPYVVTARKI
IEDHFDLLSV RDYKRLKKIY LLDDDDLMEV IHVIQALSPR PGRAYASTQN ELVIPDLRLH
RTATGYMVEL NQEAFPRLSI NRAYVDMAND LQGQSGESKQ IKEQLFEAKS LIKSIQSRGE
TLLRVGRYIV EKQARFFEEG EQAMQPMVLR DLAEALDLHE STISRATNQK YIQTPRGTFE
LKYFFSTGVS QYGSDDQSAI AIKSHIKQLI ENEDPKKPLS DNKLMQLLED KDISVARRTI
AKYREAMHIP SSSERKRMNQ YR
//
