ID A0A0X3USA5_9ACTN Unreviewed; 384 AA.
AC A0A0X3USA5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Serine protease {ECO:0000313|EMBL:KUL35448.1};
GN ORFNames=ADL12_19860 {ECO:0000313|EMBL:KUL35448.1};
OS Streptomyces regalis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL35448.1, ECO:0000313|Proteomes:UP000053923};
RN [1] {ECO:0000313|Proteomes:UP000053923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL35448.1}.
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DR EMBL; LLZG01000153; KUL35448.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0X3USA5; -.
DR OrthoDB; 9798386at2; -.
DR Proteomes; UP000053923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:KUL35448.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053923};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..384
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038661811"
FT TRANSMEM 353..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..309
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT REGION 321..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 384 AA; 39112 MW; 9D3C2F468963A469 CRC64;
MAGRTTSGPM LATRAGAVAA ALALAVVAAG TAAPADSGAL RESEWALTAL KAEQAWEITR
GEGVTVAVIG TGVDASHPDL AGRVVKSRDV DGTRDEGGGS AAIQGTHAAG VIAGTGRNFD
GDGLFGLAPK ARILPFSVYR DNTALTAATA RSIMDAARQG AEVIDVTVGF PRPSDDLKTA
IEFATDRDAL VVAGAGDTGG TGNAETYPAA YPGVLSVTAM DKKGAIWPDS HHGKDVDLAA
PGVDILTTAR NRDYWTGSGT AFAASWVAGS AALLRSEHPK WTVSQVTRTL TETATQQGKA
DWDSRYGRGV VAPAAALSQR AVPSGSEAAA PPKDQAANAE NHATSEPSDA GPALIVLAVT
TTLLVLAVIA WLLIRRSVTP TDND
//
