ID A0A0X3UV06_9ACTN Unreviewed; 299 AA.
AC A0A0X3UV06;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Short-chain dehydrogenase {ECO:0000313|EMBL:KUL36393.1};
GN ORFNames=ADL22_24565 {ECO:0000313|EMBL:KUL36393.1};
OS Streptomyces sp. NRRL F-4489.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609095 {ECO:0000313|EMBL:KUL36393.1, ECO:0000313|Proteomes:UP000053256};
RN [1] {ECO:0000313|EMBL:KUL36393.1, ECO:0000313|Proteomes:UP000053256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-4489 {ECO:0000313|EMBL:KUL36393.1,
RC ECO:0000313|Proteomes:UP000053256};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL36393.1}.
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DR EMBL; LLZI01000247; KUL36393.1; -; Genomic_DNA.
DR RefSeq; WP_066983838.1; NZ_LLZI01000247.1.
DR AlphaFoldDB; A0A0X3UV06; -.
DR STRING; 1609095.ADL22_24565; -.
DR OrthoDB; 3178062at2; -.
DR Proteomes; UP000053256; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05374; 17beta-HSD-like_SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43976:SF16; NAD(P)-BINDING PROTEIN; 1.
DR PANTHER; PTHR43976; SHORT CHAIN DEHYDROGENASE; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053256}.
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 31065 MW; D24585E6343805EB CRC64;
MTHQATAPGE EFAPTTDASE ETPVWLITGS SSGLGRALAE HALRRGDRVA VTARDTAAVA
DLAAAYGHRA LALRLDVTDP ASVTAAVEAS EKEFGRIDVL VNNAGYGYLA AIEEGEDTAV
RALYDTNVHG VVTVLKAVLP GMRARRSGRI VNISSFGGLA AFAATGYYHA TKFALEGLSE
SLAAEVAPLG ITVTIAEPGG LRTQWAGTSM RQSPIRLADY EATAGARRAS TLAVSGRQPG
DPARAAAAIA TAVDATDPPL RLLLGSDALA GARARQERTR KEIDANASLT RSTDLEQTS
//
