ID A0A0X3VAT2_9ACTN Unreviewed; 483 AA.
AC A0A0X3VAT2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Betaine-aldehyde dehydrogenase {ECO:0000313|EMBL:KUL41855.1};
GN ORFNames=ADL12_10530 {ECO:0000313|EMBL:KUL41855.1};
OS Streptomyces regalis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL41855.1, ECO:0000313|Proteomes:UP000053923};
RN [1] {ECO:0000313|Proteomes:UP000053923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL41855.1}.
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DR EMBL; LLZG01000058; KUL41855.1; -; Genomic_DNA.
DR RefSeq; WP_062701033.1; NZ_LLZG01000058.1.
DR AlphaFoldDB; A0A0X3VAT2; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000053923; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000053923}.
FT DOMAIN 17..478
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 254
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 483 AA; 50761 MW; 48B24CF7767D1AA8 CRC64;
MTTFEIEPGR LFIGGQWREA ADGARTEVVD PSRGAVVTTV ADAGAADVDA AVRAAREAFD
DGAWSGLSGR ERGRVLHRVA ELIRENADTI AELESRDVGK PITLAHAVDV TNAANDYEHF
AALAHSLDGS LRDTPMNALA YVRRRPIGVV AAITPYNFPL ILAGSKIAPA LAAGNTVVHK
PAEETPLSAL YMAELVKRAG VPDGVVNVVT GGPAAGEALL RHSGVDKVAF TGSTSVGRKV
AGIAGEALKP VTMELGGNAA HLVFEDADLE KAVGAVIKGF VFNTGQFCMG GPRLLVARPV
YSTLLGILAD AVPGVPVGDP RGPETVVGPM AGERHLRKVE EYVDLARKEG GRIVCGGERL
DLDGGYYYKP TVIADLPNDS RVIQEEIFGP VLTVQPFDSE DEAVELANST PYGLASGVQT
GNLARAHRVA DRLQAGIVWV NDWAMLDPAV PFGGVKDSGF GREYGPEALD AYSTTKSVVV
SLD
//
