ID A0A0X3VD58_9ACTN Unreviewed; 369 AA.
AC A0A0X3VD58;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Acid phosphatase {ECO:0000313|EMBL:KUL42357.1};
GN ORFNames=ADL15_00250 {ECO:0000313|EMBL:KUL42357.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL42357.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL42357.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL42357.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL42357.1}.
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DR EMBL; LLZH01000001; KUL42357.1; -; Genomic_DNA.
DR RefSeq; WP_067683670.1; NZ_LLZH01000001.1.
DR AlphaFoldDB; A0A0X3VD58; -.
DR OrthoDB; 5296884at2; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR014636; RNaseH/PGlycerate_mutase.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR PANTHER; PTHR48100:SF1; PHOSPHOGLYCERATE MUTASE PMU1-RELATED; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR PIRSF; PIRSF036922; RNaseH_PGAM; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053244}.
FT DOMAIN 3..143
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT ACT_SITE 174
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 250
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 225
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 369 AA; 39221 MW; A27D3E8F6CE94948 CRC64;
MSGDLRVVVE ADGGSRGNPG PSGYGAVVKD AVTGEVLLER YAALGTATNN VAEYSGLIAG
LRAAAELNAT RVDVRMDSKL VIEQMAGRWQ IKNSGLRPLA AEAAGLVAKF DEVTYGWIPR
ERNKDADALA NRAMDEAAGK TTPERVEREL TVPKPRSWAP PSLENATRLI LVRHGETAMT
SQGRYSGRGD VPLTDAGEAQ AMAAGGRVAG LSRDVGAVLA SPLVRCVRTA ELIAAETGGL
PVTVMDDLIE CDFGLWEGKT FAEVQEGWPR EMTAWLESTS VAPPQGESFQ TVAKRVRGAL
AKIIEAYPGQ TVVVVSHVSP IKLILRDALA AGDAFLHRLF LDAAGVSTMD VWPDGNIAVR
SVNETAHLR
//
