ID   A0A0X3VGH9_9ACTN        Unreviewed;       399 AA.
AC   A0A0X3VGH9;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KUL43362.1};
GN   ORFNames=ADL12_08100 {ECO:0000313|EMBL:KUL43362.1};
OS   Streptomyces regalis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL43362.1, ECO:0000313|Proteomes:UP000053923};
RN   [1] {ECO:0000313|Proteomes:UP000053923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL43362.1}.
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DR   EMBL; LLZG01000038; KUL43362.1; -; Genomic_DNA.
DR   RefSeq; WP_062700093.1; NZ_LLZG01000038.1.
DR   AlphaFoldDB; A0A0X3VGH9; -.
DR   OrthoDB; 3189808at2; -.
DR   Proteomes; UP000053923; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF12802; MarR_2; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01125; ROK; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053923}.
FT   DOMAIN          19..68
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000259|Pfam:PF12802"
SQ   SEQUENCE   399 AA;  40772 MW;  6076F0715AAFEE5F CRC64;
     METPGSQSSL HRANLERVVR AVRLAGSLTQ AEIARTTGLS AATVSNIVRE LKDGGTVEVT
     PTSAGGRRAR SVSLSGDAGI VIGVDFGHTH LRVAVGNLAH QVLAEESEPL DVDASSTQGF
     DRAEELVNRL IAATGVDRSK IAGVGLGVPG PIDVESGTLG STAILPGWTG TKPAEELRGR
     LGVPVHVDND ANLGALGELV WGSGRGVRDL AYIKVASGVG SGLVINGKIY RGPGGTAGEI
     GHITLDESGP VCRCGNRGCL ETFAAARYVL PLLQSSHGTD LTMEGVVRLA RDGDPGCRRV
     IADVGRHIGS GVANLCNLLN PSRVVLGGDL AEAGELVLGP IRESVGRYAI PSAARQLSVL
     PGALGGRAEV LGALALALSE MGDSTLLDST LHAATPAFT
//