ID A0A0X3VH49_9ACTN Unreviewed; 614 AA.
AC A0A0X3VH49;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Transferase {ECO:0000313|EMBL:KUL44020.1};
GN ORFNames=ADL12_05585 {ECO:0000313|EMBL:KUL44020.1};
OS Streptomyces regalis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL44020.1, ECO:0000313|Proteomes:UP000053923};
RN [1] {ECO:0000313|Proteomes:UP000053923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000256|RuleBase:RU003750}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL44020.1}.
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DR EMBL; LLZG01000025; KUL44020.1; -; Genomic_DNA.
DR RefSeq; WP_062699129.1; NZ_LLZG01000025.1.
DR AlphaFoldDB; A0A0X3VH49; -.
DR OrthoDB; 4850070at2; -.
DR Proteomes; UP000053923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR048254; CDP_ALCOHOL_P_TRANSF_CS.
DR InterPro; IPR045985; DUF5941.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR Pfam; PF19365; DUF5941; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053923};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003750};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 406..614
FT /note="DUF5941"
FT /evidence="ECO:0000259|Pfam:PF19365"
FT REGION 99..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 64028 MW; 05889F703401C200 CRC64;
MSTAILTGQP VPGSSIEGDL RSLGYDVRVA ADLADAETLL AQVPGDQRVA VVDARFVGHL
HALRLGMTDP RFPLAAIPGA VTAQPAGRQA LTRAMARENS AGGGTVDGGA PARAKPSVGD
VDSLADRIVT ALDDDGTDVH HPELGSLVAA VPADPQARNE ARQAVAGVDD EAVRLKSAVK
SRDGFFTTFF ISPYSRYIAR WCARRGLTPN QVTTASLLTA LIAAGCAATG TRGGFVAAGL
LLIFSFVLDC TDGQLARYSL QYSTLGAWLD ATFDRAKEYA YYAGLALGAA RGGDDIWALA
LGAMVLQTCR HVVDFSFNEA NHDATANTSP TAALSDKLDS VGWTVWVRRM IVLPIGERWA
MIAVLTAVTT PRITFYALLI GCAFAATYTT AGRMLRSLTR KARRTDRAAQ ALADLADSGP
LAQGLAKAFK NPARRLPRFA VPAVALLGGA AVVAAAALTD FGGPWPIVAA LVYVVTAGLA
VARPLKGALD WLVPPFFRAA EYGTVLALAV KAGVNGALPA AFGLVAAVAY HHYDTVYRIR
GNAGASPAWL VRVIGGHEGR TLLVTVLAAA LTASQFKVAL TALAVAVALV VLVESIRFWV
SSGAPAVHDE GEPA
//
