ID   A0A0X3VT75_9ACTN        Unreviewed;       379 AA.
AC   A0A0X3VT75;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Histidine kinase {ECO:0000313|EMBL:KUL47462.1};
GN   ORFNames=ADL30_36630 {ECO:0000313|EMBL:KUL47462.1};
OS   Streptomyces sp. NRRL S-1521.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL47462.1, ECO:0000313|Proteomes:UP000053420};
RN   [1] {ECO:0000313|EMBL:KUL47462.1, ECO:0000313|Proteomes:UP000053420}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL47462.1,
RC   ECO:0000313|Proteomes:UP000053420};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL47462.1}.
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DR   EMBL; LLZK01000281; KUL47462.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0X3VT75; -.
DR   Proteomes; UP000053420; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KUL47462.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053420};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        46..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        75..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          190..253
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
SQ   SEQUENCE   379 AA;  41247 MW;  EBFD2E54378E3B6D CRC64;
     MAAAQERRGP DGSWTRGQLR TWHLSTILPP LAIVGVVLVA VDARSWWEAV VLVPGLLAAM
     LVVERWTAGD ASRVALPCLI VVAAVWPLGV LVSDSHTAFY GLLIVGPYLV SQLPGNRAPA
     TLALCGYVAA VGAARLLVSR DGVVEELLRC VAIPTGATAL AVGCMIANQR FYEIIEQSRE
     REAELAVVRE RMRFASDLHD IQGHTLHVVK LKVALAEKLV HTDIDRVREE LREVRALVGD
     TISQTKELAY AQRRLNLSVE LENAKNLFEA AGIRVRVDRE ADVDDRGGEL LGQVLRETTT
     NILRHAEATR VRITLSETGI TIVNDGAGTE PVPGLGGLAA LRERVADNGG ELTVEQKDGR
     FLTSARFPRV RPGVRKDDR
//