ID A0A0X3VYJ2_9ACTN Unreviewed; 497 AA.
AC A0A0X3VYJ2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=AraC family transcriptional regulator {ECO:0000313|EMBL:KUL49728.1};
GN ORFNames=ADL22_07865 {ECO:0000313|EMBL:KUL49728.1};
OS Streptomyces sp. NRRL F-4489.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609095 {ECO:0000313|EMBL:KUL49728.1, ECO:0000313|Proteomes:UP000053256};
RN [1] {ECO:0000313|EMBL:KUL49728.1, ECO:0000313|Proteomes:UP000053256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-4489 {ECO:0000313|EMBL:KUL49728.1,
RC ECO:0000313|Proteomes:UP000053256};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL49728.1}.
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DR EMBL; LLZI01000067; KUL49728.1; -; Genomic_DNA.
DR RefSeq; WP_066975130.1; NZ_LLZI01000067.1.
DR AlphaFoldDB; A0A0X3VYJ2; -.
DR STRING; 1609095.ADL22_07865; -.
DR OrthoDB; 9811249at2; -.
DR Proteomes; UP000053256; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.10.10; DNA Methylphosphotriester Repair Domain; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR Gene3D; 1.10.1670.10; Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal); 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR035451; Ada-like_dom_sf.
DR InterPro; IPR004026; Ada_DNA_repair_Zn-bd.
DR InterPro; IPR010316; AlkA_N.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR023170; HhH_base_excis_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF13; DNA-3-METHYLADENINE GLYCOSYLASE 2; 1.
DR Pfam; PF02805; Ada_Zn_binding; 1.
DR Pfam; PF06029; AlkA_N; 1.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM01009; AlkA_N; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF57884; Ada DNA repair protein, N-terminal domain (N-Ada 10); 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF55945; TATA-box binding protein-like; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000053256};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 85..183
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 497 AA; 53569 MW; 0429C89D1C8FDF70 CRC64;
MLDFERCWRA TLSRDTRFDG LFYSAVVTTG IYCRPSCPGC PKRKNVRFYR SAAAAQDAGY
RACKRCNPDA SPGSPEWNLR ADVVGRAMRL IADGVCDREG VTGLAAQLGY TTRHLHRLLT
AEVGVGPQAL ARAQRAQTAR ILLETTSLRI TDVAMAAGFS SVRQFNDTMA AIFDRTPTAL
REMADSPAEH AAGTIVVRLS VREPFDSQAL LRFFAAHAVP GIEEIDGATY RRSLQLPRGA
GVVALTAHTG YVEAHFRLED IRDLSTAIHR CRRLLDLDAD PLAITELLAG EPVMAPLVAA
HPGLRVPGAA DPEELLLRTV LRQTLPGREG FAAAAALTRR LGRPLPSPIG AVTHLFPTAV
ALAEAPLAKM LPAEAAGLLH RVATELAAGD LTLNDGGDRA QTERQLMQAG LSGQGAAYLV
MRALKDPDVF LAQAPATGRA LHSLGQPTSL APTMRRAEHW SPWRSYALMQ LWNLHPGDFQ
LFAPAREAPS LPATLAA
//
