ID A0A0X3W5C3_9ACTN Unreviewed; 706 AA.
AC A0A0X3W5C3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ADL30_24645 {ECO:0000313|EMBL:KUL52159.1};
OS Streptomyces sp. NRRL S-1521.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL52159.1, ECO:0000313|Proteomes:UP000053420};
RN [1] {ECO:0000313|EMBL:KUL52159.1, ECO:0000313|Proteomes:UP000053420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL52159.1,
RC ECO:0000313|Proteomes:UP000053420};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL52159.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LLZK01000221; KUL52159.1; -; Genomic_DNA.
DR RefSeq; WP_062779118.1; NZ_LLZK01000221.1.
DR AlphaFoldDB; A0A0X3W5C3; -.
DR Proteomes; UP000053420; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053420};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 531..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 617..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 195..327
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 706 AA; 73392 MW; B506A20935870007 CRC64;
MLTTLARTAT RRPLTVIALW VGLLVLGLGL GARVFGDLTS TVEDVPGSES VVTDDLLDEL
DPAGASFTAV VSGGGPVDRP GLRAEVAAAV TGVRALPGVA EVPDPYATRG LVADDSRALL
IPVTLKGGLD DDAEEDAVGD AADVIRDLDG ADVAVSGGPL LGEQLGTRAQ EDVARAELIT
LPAVLLALLL IFGGLRAAGL PLLVTVSGVA GAFLILFGFS LLTDISVYAV QIVTMLGLGL
AVDYALLMVV RFREERSRGT AVAEAVHATV ARAGRTVLFS GLTVAISLSG LIWFPSPFLR
SMGLAAGAVV VVDMLAALTL LPALLARFGG KIAAPAPTAR AARGGAFFAR LARFSVARPL
AVLALVVTAL AALAVPALGM RISIGDARQL PHGTEARQLY DTVRAHYPAA VDTSPVEVLI
RPGAEAGCER RIRALPGVAA TERQRLSDGT VLLGLTPRGP SDGPTATRLV EHVRDLRGGE
PVRVTGNAAR LVDFRAMLAE RAPWAVLTVV VGLFALLFAF TGSVLIPLRT LATTLLSLAA
ALGVVTWVFQ HGHGASLLGG EGLGSLSLTA PPLIIAIAFG LAMDYELFIL SRMRESWTET
GDHRTAVVEG LRRSGRVVSC AALLLALVFA GFMTGGFSPI LQIGLGLTLA VLIDATVVRM
LLVPATMALL GRRAWWAPGP LRRLHERHGV RESAPAEAVM PGRPRP
//
