ID A0A0X3Y6Q1_9GAMM Unreviewed; 304 AA.
AC A0A0X3Y6Q1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:KUM52510.1};
DE EC=4.1.3.4 {ECO:0000313|EMBL:KUM52510.1};
GN ORFNames=AR688_09435 {ECO:0000313|EMBL:KUM52510.1};
OS Rheinheimera sp. EpRS3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Rheinheimera.
OX NCBI_TaxID=1712383 {ECO:0000313|EMBL:KUM52510.1, ECO:0000313|Proteomes:UP000054239};
RN [1] {ECO:0000313|Proteomes:UP000054239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS3 {ECO:0000313|Proteomes:UP000054239};
RA Presta L., Bosi E., Fondi M., Maida I., Maggini V., Bogani P.,
RA Firenzuoli F., Chiellini C., De Pascale D., Palma F., Di Pilato V.,
RA Rossolini G., Mengoni A., Fani R.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM52510.1}.
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DR EMBL; LNQS01000009; KUM52510.1; -; Genomic_DNA.
DR RefSeq; WP_068234815.1; NZ_LNQS01000009.1.
DR AlphaFoldDB; A0A0X3Y6Q1; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000054239; Unassembled WGS sequence.
DR GO; GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:KUM52510.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 7..273
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 304 AA; 31369 MW; 393586CCEE0FAF64 CRC64;
MSLPKSVRLV EVGPRDGLQN EAAVATEDKI ALIDMLTAAG HSYIESGAFV SPKWVPQMAD
SGEVFAGIQR KTGVTYAALT PNLKGYEAAK AAGATEVAIF GAASEAFSQK NINCSIAESL
ERFAPVVEAA KADGIKVRGY VSCVVGCPYQ GDVAPTEVAL VAKALLEMGC YEISLGDTIG
VGTPDKVNAM LDAVLSMVPV DKLAVHFHDT YGQALTNIYV ALNRGISVID SAVAGLGGCP
YAAGASGNVA TEDVVYLLNG LGISHGIDLT ALAKAGWFIT DKLGKQPSSK VGLALRAKCT
QTGS
//
