ID A0A0X8FAE2_9LACT Unreviewed; 453 AA.
AC A0A0X8FAE2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=FAD-dependent oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AWM72_01645 {ECO:0000313|EMBL:AMB93540.1}, CYJ28_07460
GN {ECO:0000313|EMBL:PKZ21731.1};
OS Aerococcus sanguinicola.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Aerococcus.
OX NCBI_TaxID=119206 {ECO:0000313|EMBL:AMB93540.1, ECO:0000313|Proteomes:UP000069912};
RN [1] {ECO:0000313|EMBL:AMB93540.1, ECO:0000313|Proteomes:UP000069912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG43001 {ECO:0000313|EMBL:AMB93540.1,
RC ECO:0000313|Proteomes:UP000069912};
RX PubMed=27103727;
RA Carkaci D., Dargis R., Nielsen X.C., Skovgaard O., Fuursted K.,
RA Christensen J.J.;
RT "Complete Genome Sequences of Aerococcus christensenii CCUG 28831T,
RT Aerococcus sanguinicola CCUG 43001T, Aerococcus urinae CCUG 36881T,
RT Aerococcus urinaeequi CCUG 28094T, Aerococcus urinaehominis CCUG 42038 BT,
RT and Aerococcus viridans CCUG 4311T.";
RL Genome Announc. 4:0-0(2016).
RN [2] {ECO:0000313|Proteomes:UP000069912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG43001 {ECO:0000313|Proteomes:UP000069912};
RA Carkaci D., Dargis R., Nielsen X.C., Skovgaard O., Fuursted K.,
RA Christensen J.J.;
RT "Six Aerococcus type strain genome sequencing and assembly using PacBio and
RT Illumina Hiseq.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:PKZ21731.1, ECO:0000313|Proteomes:UP000234239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMB0139 {ECO:0000313|EMBL:PKZ21731.1,
RC ECO:0000313|Proteomes:UP000234239};
RA Thomas-White K., Wolfe A.J.;
RT "Phylogenetic diversity of female urinary microbiome.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the class-III pyridine nucleotide-disulfide
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00009130}.
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DR EMBL; CP014160; AMB93540.1; -; Genomic_DNA.
DR EMBL; PKGY01000003; PKZ21731.1; -; Genomic_DNA.
DR RefSeq; WP_067972185.1; NZ_PKGY01000003.1.
DR AlphaFoldDB; A0A0X8FAE2; -.
DR GeneID; 69593575; -.
DR KEGG; asan:AWM72_01645; -.
DR OrthoDB; 9802028at2; -.
DR Proteomes; UP000069912; Chromosome.
DR Proteomes; UP000234239; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
DR PANTHER; PTHR43429:SF1; COENZYME A DISULFIDE REDUCTASE; 1.
DR PANTHER; PTHR43429; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF02852; Pyr_redox_dim; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
PE 3: Inferred from homology;
KW Oxidation {ECO:0000256|ARBA:ARBA00023097};
KW Reference proteome {ECO:0000313|Proteomes:UP000069912}.
FT DOMAIN 1..303
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 330..430
FT /note="Pyridine nucleotide-disulphide oxidoreductase
FT dimerisation"
FT /evidence="ECO:0000259|Pfam:PF02852"
SQ SEQUENCE 453 AA; 49830 MW; E587737B5F6C6114 CRC64;
MKVVVVGTSH AGYEMVQTLL KADQDIEIDL YESGSTMSFL SCGIQSYLEG KSDHLDDLHY
ATEDSYKKQG INAYTNSQVV AIDSDAKEVT VKDDQGEHQV SYDKLFLSPG AVPVELPIEG
TDLDHVYYLR GRDWADRVKK RMAEAKEAVV VGGGYIGIEA AEAFTKAGIK TTVIDSQDRI
LPTYLDKEFT EVLEAHAADK GLDFHGNECV QSIEGKDGQV AKVITDKGEY PADTVLFAVG
VKPNTEWLKG TLELDDKGFV KVNEYLESSV KDIYVAGDAT EIPFTPTGKG KAIALASNAR
RQAVTAAQNI IAGENKVKSP SVNGTSGLAL FDYHFAATGV KDCDKAEVDG EVESQFLQIP
VLPKFMKDDQ DVFMKIHYRK DDHKLVGAQI MSTVNLARDI NTLSVAISAG WTLEDLALAD
FFFQPEYDNT WHYFNQVAQE ALGQRFGSDK QLF
//
