ID A0A0X8GR91_9BURK Unreviewed; 376 AA.
AC A0A0X8GR91;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=VN23_20270 {ECO:0000313|EMBL:AMC36756.1};
OS Janthinobacterium sp. B9-8.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=1236179 {ECO:0000313|EMBL:AMC36756.1, ECO:0000313|Proteomes:UP000069577};
RN [1] {ECO:0000313|EMBL:AMC36756.1, ECO:0000313|Proteomes:UP000069577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B9-8 {ECO:0000313|EMBL:AMC36756.1,
RC ECO:0000313|Proteomes:UP000069577};
RA Xu X., Jin W., Wu Q., Jiang L., Huang H.;
RT "The whole genome sequence of Janthinbacterium sp. B9-8, a bacterium
RT isolated from low temperature sewage.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR EMBL; CP014222; AMC36756.1; -; Genomic_DNA.
DR RefSeq; WP_046350456.1; NZ_CP014222.1.
DR AlphaFoldDB; A0A0X8GR91; -.
DR STRING; 1236179.VN23_20270; -.
DR KEGG; jab:VN23_20270; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000069577; Chromosome.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513}.
FT DOMAIN 22..369
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 376 AA; 41935 MW; 1DE0594982B77517 CRC64;
MKKILVVFGT RPEAIKMAPL VRELKQRSEF ETRVCVTAQH RQMLDQVLEL FSIVPEYDLN
LMQPGQDLSD ITSRILLALK PVFEDFKPDL VLVHGDTTTS MACSLSAFYH RIRVGHIEAG
LRTGDIYSPW PEELNRKITS LMAWMHFAPT EIAKNNLLNE GIKEESICIT GNTVIDALLA
TSKQIDLDST LSAKLHQKFS FIDKSKKLIL VTGHRRENFG QGFENICAAL SVLAIRDDVQ
VVYPVHLNPN VQVPVNKYLS NSENIYLIDP QDYLPFVYLM KQSFLILTDS GGIQEEAPSL
GKPVLVMRDT TERPEAVLAG TVMLTGANTS RIIDGVENLL KEGKDYQQMT AAHNPYGTGN
ACKTIVDSLS SSLAEK
//
