ID A0A0X8GYF9_9FIRM Unreviewed; 322 AA.
AC A0A0X8GYF9;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=phosphomevalonate kinase {ECO:0000256|ARBA:ARBA00012958};
DE EC=2.7.4.2 {ECO:0000256|ARBA:ARBA00012958};
GN ORFNames=AOC36_01645 {ECO:0000313|EMBL:AMC92735.1};
OS Erysipelothrix larvae.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Erysipelotrichaceae; Erysipelothrix.
OX NCBI_TaxID=1514105 {ECO:0000313|EMBL:AMC92735.1, ECO:0000313|Proteomes:UP000063781};
RN [1] {ECO:0000313|EMBL:AMC92735.1, ECO:0000313|Proteomes:UP000063781}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LV19 {ECO:0000313|EMBL:AMC92735.1,
RC ECO:0000313|Proteomes:UP000063781};
RA Lim S., Kim B.-C.;
RT "Erysipelothrix larvae sp. LV19 isolated from the larval gut of the
RT rhinoceros beetle, Trypoxylus dichotomus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis
CC via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate:
CC step 2/3. {ECO:0000256|ARBA:ARBA00005017}.
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DR EMBL; CP013213; AMC92735.1; -; Genomic_DNA.
DR RefSeq; WP_067630514.1; NZ_CP013213.1.
DR AlphaFoldDB; A0A0X8GYF9; -.
DR STRING; 1514105.AOC36_01645; -.
DR KEGG; erl:AOC36_01645; -.
DR OrthoDB; 1522677at2; -.
DR UniPathway; UPA00057; UER00099.
DR Proteomes; UP000063781; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004631; F:phosphomevalonate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019287; P:isopentenyl diphosphate biosynthetic process, mevalonate pathway; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR035102; Phosphomevalonate_kinase.
DR InterPro; IPR005917; Pmev_kinase_bact.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR01220; Pmev_kin_Gr_pos; 1.
DR PANTHER; PTHR31814; -; 1.
DR PANTHER; PTHR31814:SF2; PHOSPHOMEVALONATE KINASE; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000063781};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 102..158
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 255..316
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 322 AA; 36649 MW; 3A5202EEBDBFCDA7 CRC64;
MIEVKHPGKL YVMGEYSVMQ PGNSAVLIAV KQKMITRIEA SPETRIETQY GTFRPQHSDE
KSLRYVKQAY EVCEAYLRFK QVSFKPFKMK ITSTLDVEGK KYGFGSSGVV IVSVLDAMLH
YHALNVDALT LFKLSVYTQY LMHEMSSGGD IAVAVYGQSL AYTRYDTACV TADIRCVEME
WNQLMIQPLK LDVDIFVGWT QSPYKTPDAL NHAKRFETLY PDAYVKRCDE AQEIVMGFIS
NPQNLKYIDM YRDWMRSFQK WTHQAIETEQ LTHLIQSAQD CGFVAKVSGA GGGDCGIALG
RDLDPTPLYR EWEKHGIIPV EI
//
