ID A0A0X8HFP7_9GAMM Unreviewed; 888 AA.
AC A0A0X8HFP7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cyclic di-GMP phosphodiesterase Gmr {ECO:0000313|EMBL:AMD01801.1};
DE EC=3.1.4.52 {ECO:0000313|EMBL:AMD01801.1};
GN Name=gmr_7 {ECO:0000313|EMBL:AMD01801.1};
GN ORFNames=LOKO_02749 {ECO:0000313|EMBL:AMD01801.1};
OS Halomonas chromatireducens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=507626 {ECO:0000313|EMBL:AMD01801.1, ECO:0000313|Proteomes:UP000063387};
RN [1] {ECO:0000313|EMBL:AMD01801.1, ECO:0000313|Proteomes:UP000063387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD01801.1,
RC ECO:0000313|Proteomes:UP000063387};
RX PubMed=26988058;
RA Sharko F.S., Shapovalova A.A., Tsygankova S.V., Komova A.V.,
RA Boulygina E.S., Teslyuk A.B., Gotovtsev P.M., Namsaraev Z.B.,
RA Khijniak T.V., Nedoluzhko A.V., Vasilov R.G.;
RT "Draft Genome Sequence of 'Halomonas chromatireducens' Strain AGD 8-3, a
RT Haloalkaliphilic Chromate- and Selenite-Reducing Gammaproteobacterium.";
RL Genome Announc. 4:0-0(2016).
RN [2] {ECO:0000313|EMBL:AMD01801.1, ECO:0000313|Proteomes:UP000063387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD01801.1,
RC ECO:0000313|Proteomes:UP000063387};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014226; AMD01801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0X8HFP7; -.
DR STRING; 507626.LOKO_02749; -.
DR KEGG; hco:LOKO_02749; -.
DR PATRIC; fig|507626.3.peg.2743; -.
DR OrthoDB; 9804951at2; -.
DR Proteomes; UP000063387; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071111; F:cyclic-guanylate-specific phosphodiesterase activity; IEA:UniProtKB-EC.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12915; PDC2_DGC_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AMD01801.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000063387};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 274..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 340..371
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 398..450
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 482..620
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 629..883
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 888 AA; 99070 MW; 9BD95D7BC6C44DEB CRC64;
MIYTMAVTLV LLVIVWALKE RHDRELDAAE GRVLAQAELM AEWASGTFNS TDNTLSGLAN
LFALSIDGDI DQRFARAFES LVSQRQQSLP FLDALGIISH TGETLYTIGN PGFPGHDMEE
RAFIRRFLQD YDQSHSDSYW NPESGDHRML YLRRMFDADG FFLGVAAARL DLFFLTHALQ
RLTLDPGESI AFIDGNLRLI ARRPDLESLP MTQALGMQVD APAVAELIAG DRSGAVTIRS
PLAGDSRIFG IGRVEGMPIV AAVGFSVRSV LASWYQQVVI LTFGWLLTAA LGLLILLHYL
RLSRTEAELQ CSEQALRQIN HSLQAELRIA DMAFETHLGM FITDADGIIR KVNVTFERIT
GYSADEVLGE NPRLLNSGRH DASFYREMWG SIHEKGSWQG EVWNRRKNGD TYPQWVTISA
VKDVQGEVTH YVATISDLTH RKAAEQEAHR LAFFDPLTGL PNRRMLLDRL AEALEASRQS
EQQSVLLFID LDGFKHINDS LGHQLGDELL QLMARRIQAV SRDVDLVARL GGDEFVILAE
SLGETIDGTS QAAERLATKL LGKLTQPCWL GERRHLLSGS IGITLLGDGV GRAEECLQQA
EMAMYQAKQA GRNTLRFFDP VMQAVAVRRA MIESDLRQAA RRDELKLFYQ IQVDGKSQVT
GVEALLRWEH PEHGMIPPND FIPVAEESYL IVSIGNWVLE TACRQLARWA SDPRTAELTM
AINISPLQFQ QPDFVASLSA VLETTGARPE RLKLELTETL FMEEPEAVRE TMRRVQAMGV
CFSLDDFGTG YSSLSYLSCL PLDQLKIDQS FVRTLFQDVS NEMICATIIS LGRNLGLEVI
AEGVETQAHR DWLEAHGCHA YQGYLYSRPL PIHALTGLLE SSTCAAGR
//
